Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3833308..3833813 Replicon chromosome
Accession NZ_CP099530
Organism Xanthomonas sacchari strain YT9-19-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NG828_RS16250 Protein ID WP_267081873.1
Coordinates 3833556..3833813 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6N7Q778
Locus tag NG828_RS16245 Protein ID WP_017907919.1
Coordinates 3833308..3833559 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG828_RS16230 (NG828_16195) 3828488..3831700 + 3213 WP_267081871.1 error-prone DNA polymerase -
NG828_RS16235 (NG828_16200) 3831850..3832161 - 312 WP_150410534.1 hypothetical protein -
NG828_RS16240 (NG828_16205) 3832395..3833144 - 750 WP_267081872.1 endonuclease -
NG828_RS16245 (NG828_16210) 3833308..3833559 + 252 WP_017907919.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NG828_RS16250 (NG828_16215) 3833556..3833813 + 258 WP_267081873.1 Txe/YoeB family addiction module toxin Toxin
NG828_RS16260 (NG828_16225) 3834079..3834432 - 354 WP_010342469.1 PilZ domain-containing protein -
NG828_RS16265 (NG828_16230) 3834429..3835391 - 963 WP_153751171.1 DNA polymerase III subunit delta' -
NG828_RS16270 (NG828_16235) 3835388..3836059 - 672 WP_017917512.1 dTMP kinase -
NG828_RS16275 (NG828_16240) 3836056..3837117 - 1062 WP_267081874.1 endolytic transglycosylase MltG -
NG828_RS16280 (NG828_16245) 3837192..3838541 - 1350 WP_267081875.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10237.77 Da        Isoelectric Point: 9.6589

>T249078 WP_267081873.1 NZ_CP099530:3833556-3833813 [Xanthomonas sacchari]
VTLQFSDNAWEDYLYWQQADKKMLKRINDLIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKVEHGILLIAQV
RYHYV

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9324.59 Da        Isoelectric Point: 5.1186

>AT249078 WP_017907919.1 NZ_CP099530:3833308-3833559 [Xanthomonas sacchari]
MDTITYSAARAALADTMDRVVNNHEPVIITRSREQAVVMLSLEDYKAMEETAYLLRSPKNAQRLLESIAQLESGRGKARE
LSE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7Q778

References