249047

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 1095801..1096620 Replicon chromosome
Accession NZ_CP099513
Organism Klebsiella sp. ZYC-1

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag NDO58_RS05070 Protein ID WP_004132607.1
Coordinates 1095801..1096058 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag NDO58_RS05075 Protein ID WP_004132606.1
Coordinates 1096069..1096620 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDO58_RS05055 (NDO58_05055) 1091568..1092344 - 777 WP_024359123.1 Uxu operon transcriptional regulator -
NDO58_RS05060 (NDO58_05060) 1092481..1093956 - 1476 WP_024359122.1 fructuronate reductase -
NDO58_RS05065 (NDO58_05065) 1094033..1095217 - 1185 WP_024359121.1 mannonate dehydratase -
NDO58_RS05070 (NDO58_05070) 1095801..1096058 + 258 WP_004132607.1 YjhX family toxin Toxin
NDO58_RS05075 (NDO58_05075) 1096069..1096620 + 552 WP_004132606.1 N-acetyltransferase Antitoxin
NDO58_RS05080 (NDO58_05080) 1096734..1097138 + 405 Protein_969 class I SAM-dependent methyltransferase -
NDO58_RS05085 (NDO58_05085) 1097520..1098266 + 747 WP_257999610.1 class I SAM-dependent methyltransferase -
NDO58_RS05090 (NDO58_05090) 1098370..1099710 - 1341 WP_049085654.1 carbohydrate porin -
NDO58_RS05095 (NDO58_05095) 1099834..1101231 - 1398 WP_024359118.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T249047 WP_004132607.1 NZ_CP099513:1095801-1096058 [Klebsiella sp. ZYC-1]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT249047 WP_004132606.1 NZ_CP099513:1096069-1096620 [Klebsiella sp. ZYC-1]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References