Detailed information of TA system TA248602

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-sokC/Ldr(toxin)
• Location: 2501211..2501434
• Replicon: chromosome
• Accession: NZ_CP099351
• Organism: Escherichia marmotae strain RHB02-E4-C07

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: J7R083
• Locus tag: NFJ26_RS11805
• Protein ID: WP_000170963.1
• Coordinates: 2501327..2501434 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	sokC
Locus tag	-
Coordinates	2501211..2501277 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NFJ26_RS11780	2496491..2497885	-	1395	WP_000087125.1	YchO/YchP family invasin	-
NFJ26_RS11785	2498069..2498422	+	354	WP_001169672.1	DsrE/F sulfur relay family protein YchN	-
NFJ26_RS11790	2498466..2499161	-	696	WP_016248767.1	glutathione-specific gamma-glutamylcyclotransferase	-
NFJ26_RS11795	2499319..2499549	-	231	WP_001146437.1	putative cation transport regulator ChaB	-
NFJ26_RS11800	2499818..2500918	+	1101	WP_010375735.1	sodium-potassium/proton antiporter ChaA	-
-	2501211..2501277	-	67	-	-	Antitoxin
NFJ26_RS11805	2501327..2501434	+	108	WP_000170963.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
NFJ26_RS11810	2501614..2502468	-	855	WP_000811071.1	3-deoxy-8-phosphooctulonate synthase	-
NFJ26_RS11815	2502504..2503313	-	810	WP_001257034.1	invasion regulator SirB1	-
NFJ26_RS11820	2503317..2503709	-	393	WP_000200357.1	invasion regulator SirB2	-
NFJ26_RS11825	2503706..2504539	-	834	WP_000456440.1	peptide chain release factor N(5)-glutamine methyltransferase	-
NFJ26_RS11830	2504539..2505621	-	1083	WP_000804714.1	peptide chain release factor 1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3971.74 Da
• Isoelectric Point: 11.4779

>T248602 WP_000170963.1 NZ_CP099351:2501327-2501434 [Escherichia marmotae]
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT248602 NZ_CP099351:c2501277-2501211 [Escherichia marmotae]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTGACCTCTCAACGTGCGGGGGTTTTCT

Structures

Antitoxin