Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 477906..478422 Replicon chromosome
Accession NZ_CP099327
Organism Enterobacter ludwigii strain RHB47-SO-C03

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFL62_RS02305 Protein ID WP_148576588.1
Coordinates 478138..478422 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFL62_RS02300 Protein ID WP_108647582.1
Coordinates 477906..478148 (+) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFL62_RS02285 (NFL62_02290) 473903..474643 + 741 WP_014168382.1 KDGP aldolase family protein -
NFL62_RS02290 (NFL62_02295) 474762..475898 + 1137 WP_279257988.1 lactonase family protein -
NFL62_RS02295 (NFL62_02300) 475918..477828 + 1911 WP_014168384.1 PRD domain-containing protein -
NFL62_RS02300 (NFL62_02305) 477906..478148 + 243 WP_108647582.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NFL62_RS02305 (NFL62_02310) 478138..478422 + 285 WP_148576588.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFL62_RS02310 (NFL62_02315) 478426..478890 - 465 WP_047954963.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFL62_RS02315 (NFL62_02320) 479029..481167 - 2139 WP_047954964.1 anaerobic ribonucleoside-triphosphate reductase -
NFL62_RS02320 (NFL62_02325) 481535..482107 - 573 WP_032679517.1 PTS sugar transporter subunit IIA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 95 a.a.        Molecular weight: 10863.65 Da        Isoelectric Point: 10.3193

>T248458 WP_148576588.1 NZ_CP099327:478138-478422 [Enterobacter ludwigii]
MSYELVFDPRAFKEWTRLGDTVKNQFKKKLANVLVNPRVESARLYGLPDCDKIKLRSQGYRLVYQVHDNVVTVCVIAIGK
REKSAVSHDVNKRL

Download         Length: 285 bp


Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9099.52 Da        Isoelectric Point: 5.1231

>AT248458 WP_108647582.1 NZ_CP099327:477906-478148 [Enterobacter ludwigii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDELIQTVRERLANPQKGIKVRLDEL

Download         Length: 243 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References