Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2020060..2020205 | Replicon | chromosome |
| Accession | NZ_CP098770 | ||
| Organism | Klebsiella pneumoniae strain TH12845 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2020096..2020198 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2020060..2020205 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NE242_RS09910 (NE242_09910) | 2015190..2017250 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NE242_RS09915 (NE242_09915) | 2017254..2017913 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NE242_RS09920 (NE242_09920) | 2017992..2018222 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NE242_RS09925 (NE242_09925) | 2018335..2018709 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NE242_RS09930 (NE242_09930) | 2018713..2019582 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| NE242_RS09935 (NE242_09935) | 2019599..2019937 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2020060..2020205 | - | 146 | - | - | Antitoxin |
| - | 2020096..2020198 | + | 103 | - | - | Toxin |
| NE242_RS09940 (NE242_09940) | 2020573..2020716 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NE242_RS09945 (NE242_09945) | 2020821..2021789 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NE242_RS09950 (NE242_09950) | 2021946..2022599 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| NE242_RS09955 (NE242_09955) | 2022596..2022787 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NE242_RS09960 (NE242_09960) | 2022885..2023124 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NE242_RS09965 (NE242_09965) | 2023240..2024673 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T248046 NZ_CP098770:2020096-2020198 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT248046 NZ_CP098770:c2020205-2020060 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
