Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2026587..2026732 | Replicon | chromosome |
| Accession | NZ_CP098769 | ||
| Organism | Klebsiella pneumoniae strain TH12846 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2026623..2026725 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2026587..2026732 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NE243_RS09925 (NE243_09925) | 2021718..2023777 | + | 2060 | Protein_1940 | oligopeptidase B | - |
| NE243_RS09930 (NE243_09930) | 2023781..2024440 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NE243_RS09935 (NE243_09935) | 2024519..2024749 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NE243_RS09940 (NE243_09940) | 2024862..2025236 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NE243_RS09945 (NE243_09945) | 2025240..2026109 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| NE243_RS09950 (NE243_09950) | 2026126..2026464 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2026587..2026732 | - | 146 | - | - | Antitoxin |
| - | 2026623..2026725 | + | 103 | - | - | Toxin |
| NE243_RS09955 (NE243_09955) | 2027100..2027243 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NE243_RS09960 (NE243_09960) | 2027348..2028316 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NE243_RS09965 (NE243_09965) | 2028473..2029126 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| NE243_RS09970 (NE243_09970) | 2029123..2029314 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NE243_RS09975 (NE243_09975) | 2029412..2029651 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NE243_RS09980 (NE243_09980) | 2029767..2031200 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T248032 NZ_CP098769:2026623-2026725 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT248032 NZ_CP098769:c2026732-2026587 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
