Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012882..2013027 Replicon chromosome
Accession NZ_CP098159
Organism Klebsiella pneumoniae strain Z0117KP0008

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012918..2013020 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012882..2013027 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY40_RS09655 2008012..2010072 + 2061 WP_004148850.1 oligopeptidase B -
NBY40_RS09660 2010076..2010735 - 660 WP_032435029.1 exodeoxyribonuclease X -
NBY40_RS09665 2010814..2011044 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NBY40_RS09670 2011157..2011531 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NBY40_RS09675 2011535..2012404 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
NBY40_RS09680 2012421..2012759 + 339 WP_002911404.1 YebY family protein -
- 2012882..2013027 - 146 - - Antitoxin
- 2012918..2013020 + 103 - - Toxin
NBY40_RS09685 2013395..2013538 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NBY40_RS09690 2013643..2014611 - 969 WP_004151446.1 VirK/YbjX family protein -
NBY40_RS09695 2014768..2015421 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
NBY40_RS09700 2015418..2015609 - 192 WP_002911395.1 YebW family protein -
NBY40_RS09705 2015707..2015946 - 240 WP_002911393.1 YebV family protein -
NBY40_RS09710 2016062..2017495 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246728 NZ_CP098159:2012918-2013020 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246728 NZ_CP098159:c2013027-2012882 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References