Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1681035..1681566 Replicon chromosome
Accession NZ_CP097807
Organism Thalassospira sp. GO-4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag M9H61_RS07930 Protein ID WP_250284356.1
Coordinates 1681035..1681331 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag M9H61_RS07935 Protein ID WP_228194201.1
Coordinates 1681321..1681566 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9H61_RS07900 (M9H61_07900) 1676529..1676999 - 471 WP_250284349.1 helix-turn-helix domain-containing protein -
M9H61_RS07905 (M9H61_07905) 1677136..1677624 - 489 WP_250284351.1 3TM-type holin -
M9H61_RS07910 (M9H61_07910) 1677637..1678113 - 477 WP_250284352.1 cell wall hydrolase -
M9H61_RS07915 (M9H61_07915) 1678106..1678420 - 315 WP_068517888.1 hypothetical protein -
M9H61_RS07920 (M9H61_07920) 1678737..1679042 - 306 WP_068517887.1 hypothetical protein -
M9H61_RS07925 (M9H61_07925) 1679335..1680879 - 1545 WP_250284354.1 phage terminase large subunit -
M9H61_RS07930 (M9H61_07930) 1681035..1681331 - 297 WP_250284356.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M9H61_RS07935 (M9H61_07935) 1681321..1681566 - 246 WP_228194201.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
M9H61_RS07940 (M9H61_07940) 1681737..1682054 - 318 WP_250284357.1 hypothetical protein -
M9H61_RS07945 (M9H61_07945) 1682064..1683161 - 1098 WP_250284359.1 hypothetical protein -
M9H61_RS07950 (M9H61_07950) 1683255..1684691 - 1437 WP_250284361.1 hypothetical protein -
M9H61_RS07955 (M9H61_07955) 1684696..1685145 - 450 WP_250284363.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1674429..1696267 21838


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-93)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11411.96 Da        Isoelectric Point: 9.4027

>T246259 WP_250284356.1 NZ_CP097807:c1681331-1681035 [Thalassospira sp. GO-4]
MAVNAGYRLTPRAEADLEDIWRYTHRRWSVTQADKYIRDFLGVFSELAASKRIGQKCDVREGYFQTPVGAHVIYYRQASD
AIEVVRVLHGRMDVNRHL

Download         Length: 297 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8687.68 Da        Isoelectric Point: 6.2179

>AT246259 WP_228194201.1 NZ_CP097807:c1681566-1681321 [Thalassospira sp. GO-4]
MARNTSVSLGEHFNGFIDGQVKSGRYGSASDVVRAGLRLLEEHEAKVKALQEALIDGEQSGPAKPFDGDAFLTRMKTEHG
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References