Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2490143..2490732 Replicon chromosome
Accession NZ_CP097804
Organism Xanthomonas oryzae pv. oryzae strain FY517

Toxin (Protein)


Gene name graT Uniprot ID G7TIR7
Locus tag M9500_RS11845 Protein ID WP_012443754.1
Coordinates 2490143..2490424 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag M9500_RS11850 Protein ID WP_011260746.1
Coordinates 2490442..2490732 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9500_RS11840 (M9500_11840) 2487796..2490048 + 2253 WP_069960050.1 exodeoxyribonuclease V subunit alpha -
M9500_RS11845 (M9500_11845) 2490143..2490424 + 282 WP_012443754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M9500_RS11850 (M9500_11850) 2490442..2490732 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
M9500_RS11855 (M9500_11855) 2491661..2493055 + 1395 WP_027703652.1 type III secretion system effector XopQ -
M9500_RS11860 (M9500_11860) 2493158..2493345 - 188 Protein_2265 hypothetical protein -
M9500_RS11865 (M9500_11865) 2493505..2493837 - 333 WP_011260743.1 hypothetical protein -
M9500_RS11870 (M9500_11870) 2494092..2494418 + 327 WP_228329596.1 hypothetical protein -
M9500_RS11875 (M9500_11875) 2494546..2494968 + 423 WP_042465811.1 PAAR domain-containing protein -
M9500_RS11880 (M9500_11880) 2494971..2495579 + 609 WP_113195694.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11066.83 Da        Isoelectric Point: 10.5318

>T246254 WP_012443754.1 NZ_CP097804:2490143-2490424 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT246254 WP_011260746.1 NZ_CP097804:2490442-2490732 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GFW5

Antitoxin

Source ID Structure

References