Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1976985..1977130 Replicon chromosome
Accession NZ_CP097703
Organism Klebsiella pneumoniae strain IR12197_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1977021..1977123 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1976985..1977130 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3X87_RS09645 (M3X87_09645) 1972115..1974175 + 2061 WP_004151449.1 oligopeptidase B -
M3X87_RS09650 (M3X87_09650) 1974179..1974838 - 660 WP_002911407.1 exodeoxyribonuclease X -
M3X87_RS09655 (M3X87_09655) 1974917..1975147 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M3X87_RS09660 (M3X87_09660) 1975260..1975634 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M3X87_RS09665 (M3X87_09665) 1975638..1976507 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
M3X87_RS09670 (M3X87_09670) 1976524..1976862 + 339 WP_002911404.1 YebY family protein -
- 1976985..1977130 - 146 - - Antitoxin
- 1977021..1977123 + 103 - - Toxin
M3X87_RS09675 (M3X87_09675) 1977498..1977641 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M3X87_RS09680 (M3X87_09680) 1977746..1978714 - 969 WP_004151446.1 VirK/YbjX family protein -
M3X87_RS09685 (M3X87_09685) 1978871..1979523 + 653 Protein_1894 protein-serine/threonine phosphatase -
M3X87_RS09690 (M3X87_09690) 1979520..1979711 - 192 WP_002911395.1 YebW family protein -
M3X87_RS09695 (M3X87_09695) 1979809..1980048 - 240 WP_002911393.1 YebV family protein -
M3X87_RS09700 (M3X87_09700) 1980164..1981597 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1972148..1990199 18051


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246022 NZ_CP097703:1977021-1977123 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246022 NZ_CP097703:c1977130-1976985 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References