Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yxiD-yxxD/- |
| Location | 1836120..1837102 | Replicon | chromosome |
| Accession | NC_013791 | ||
| Organism | Bacillus pseudofirmus OF4 | ||
Toxin (Protein)
| Gene name | yxiD | Uniprot ID | - |
| Locus tag | BPOF4_RS21645 | Protein ID | WP_087943511.1 |
| Coordinates | 1836560..1837102 (-) | Length | 181 a.a. |
Antitoxin (Protein)
| Gene name | yxxD | Uniprot ID | D3FRA7 |
| Locus tag | BPOF4_RS09190 | Protein ID | WP_012958860.1 |
| Coordinates | 1836120..1836560 (-) | Length | 147 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BPOF4_RS09155 | 1832260..1832778 | - | 519 | WP_012958853.1 | hypothetical protein | - |
| BPOF4_RS09160 | 1832992..1833540 | - | 549 | WP_012958854.1 | DUF4240 domain-containing protein | - |
| BPOF4_RS09165 | 1833608..1834066 | - | 459 | WP_012958855.1 | hypothetical protein | - |
| BPOF4_RS09170 | 1834149..1834613 | - | 465 | WP_012958856.1 | SMI1/KNR4 family protein | - |
| BPOF4_RS09175 | 1834739..1835056 | - | 318 | WP_012958857.1 | hypothetical protein | - |
| BPOF4_RS09180 | 1835226..1835645 | - | 420 | WP_012958858.1 | SMI1/KNR4 family protein | - |
| BPOF4_RS09185 | 1835762..1836112 | - | 351 | WP_012958859.1 | YrhA family protein | - |
| BPOF4_RS09190 | 1836120..1836560 | - | 441 | WP_012958860.1 | SMI1/KNR4 family protein | Antitoxin |
| BPOF4_RS21645 | 1836560..1837102 | - | 543 | WP_087943511.1 | HNH endonuclease | Toxin |
| BPOF4_RS09200 | 1837906..1838367 | - | 462 | WP_012958862.1 | hypothetical protein | - |
| BPOF4_RS21650 | 1838381..1839883 | - | 1503 | WP_012958863.1 | hypothetical protein | - |
| BPOF4_RS09215 | 1840413..1841108 | + | 696 | WP_012958864.1 | hypothetical protein | - |
| BPOF4_RS09220 | 1841129..1841518 | + | 390 | WP_012958865.1 | NUDIX domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 1830716..1832065 | 1349 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 181 a.a. Molecular weight: 20642.44 Da Isoelectric Point: 10.4727
>T24538 WP_087943511.1 NC_013791:c1837102-1836560 [Bacillus pseudofirmus OF4]
IPHNVINTNGMRNQLGEINQANLIKVEQGAGVRSGKRVDSETIKKYIRDMEGRTGRELPKNQIENLKAALRNKEYKKMSP
VETAKHRVVFDRVKNKVIKDWEVNTGQQWPVYNENVISEKTGRIIRRKGDKYDAHHIIENTFGGEHEWWNMHPAKFPTEH
QAGIHGSGSPANILFKGVKQ
IPHNVINTNGMRNQLGEINQANLIKVEQGAGVRSGKRVDSETIKKYIRDMEGRTGRELPKNQIENLKAALRNKEYKKMSP
VETAKHRVVFDRVKNKVIKDWEVNTGQQWPVYNENVISEKTGRIIRRKGDKYDAHHIIENTFGGEHEWWNMHPAKFPTEH
QAGIHGSGSPANILFKGVKQ
Download Length: 543 bp
>T24538 NC_013791:c1837102-1836560 [Bacillus pseudofirmus OF4]
ATCCCACACAACGTCATCAATACAAACGGGATGAGAAACCAGCTAGGTGAGATAAACCAAGCGAACTTGATTAAGGTTGA
GCAAGGAGCTGGGGTACGGAGTGGTAAAAGGGTAGATTCTGAGACAATAAAAAAATATATAAGAGATATGGAAGGCAGAA
CAGGAAGAGAATTACCCAAAAATCAAATAGAGAATTTGAAGGCTGCTTTAAGAAATAAAGAATATAAAAAAATGTCTCCA
GTTGAAACAGCAAAGCACAGGGTAGTTTTTGATAGAGTAAAAAACAAAGTTATCAAAGATTGGGAAGTAAACACAGGACA
ACAGTGGCCAGTGTATAACGAAAATGTAATTTCAGAAAAAACAGGTAGAATTATTCGGAGAAAAGGAGACAAATATGATG
CTCATCATATAATTGAAAATACTTTTGGAGGAGAACACGAATGGTGGAATATGCACCCAGCAAAATTCCCTACTGAGCAT
CAAGCTGGAATTCATGGATCAGGGTCGCCAGCAAATATACTTTTTAAAGGAGTTAAACAATAA
ATCCCACACAACGTCATCAATACAAACGGGATGAGAAACCAGCTAGGTGAGATAAACCAAGCGAACTTGATTAAGGTTGA
GCAAGGAGCTGGGGTACGGAGTGGTAAAAGGGTAGATTCTGAGACAATAAAAAAATATATAAGAGATATGGAAGGCAGAA
CAGGAAGAGAATTACCCAAAAATCAAATAGAGAATTTGAAGGCTGCTTTAAGAAATAAAGAATATAAAAAAATGTCTCCA
GTTGAAACAGCAAAGCACAGGGTAGTTTTTGATAGAGTAAAAAACAAAGTTATCAAAGATTGGGAAGTAAACACAGGACA
ACAGTGGCCAGTGTATAACGAAAATGTAATTTCAGAAAAAACAGGTAGAATTATTCGGAGAAAAGGAGACAAATATGATG
CTCATCATATAATTGAAAATACTTTTGGAGGAGAACACGAATGGTGGAATATGCACCCAGCAAAATTCCCTACTGAGCAT
CAAGCTGGAATTCATGGATCAGGGTCGCCAGCAAATATACTTTTTAAAGGAGTTAAACAATAA
Antitoxin
Download Length: 147 a.a. Molecular weight: 17513.66 Da Isoelectric Point: 3.9421
>AT24538 WP_012958860.1 NC_013791:c1836560-1836120 [Bacillus pseudofirmus OF4]
MNYDFIMVNEENTFYSVSKDEIKEVEKELNLIFPRELVNFLNEIGYGFIKGSEYNINRIMDPYSIRDFRLRVNDFEFYPD
IEIYDAFENDKLIFFEGSESALMSIELNKSDTNPIYYYDIKIADSLKEFLSKIEINDQYYLDLITD
MNYDFIMVNEENTFYSVSKDEIKEVEKELNLIFPRELVNFLNEIGYGFIKGSEYNINRIMDPYSIRDFRLRVNDFEFYPD
IEIYDAFENDKLIFFEGSESALMSIELNKSDTNPIYYYDIKIADSLKEFLSKIEINDQYYLDLITD
Download Length: 441 bp
>AT24538 NC_013791:c1836560-1836120 [Bacillus pseudofirmus OF4]
ATGAATTATGATTTTATTATGGTAAACGAAGAAAACACATTCTATTCAGTGTCTAAAGATGAAATTAAGGAGGTTGAAAA
GGAACTTAATTTAATATTCCCAAGAGAGTTAGTCAACTTTCTTAATGAGATTGGTTACGGTTTTATTAAAGGGTCAGAGT
ATAATATTAATCGTATTATGGACCCTTACTCAATAAGAGATTTCCGTTTAAGAGTTAATGATTTTGAGTTCTATCCTGAC
ATTGAAATATATGATGCATTTGAAAATGATAAACTAATATTTTTTGAAGGTAGTGAATCAGCTTTAATGTCTATAGAATT
AAATAAAAGCGACACGAATCCAATTTATTATTATGACATTAAAATTGCAGACTCTCTTAAAGAGTTTTTAAGTAAGATAG
AAATTAATGATCAATATTACTTAGATTTAATTACAGATTAA
ATGAATTATGATTTTATTATGGTAAACGAAGAAAACACATTCTATTCAGTGTCTAAAGATGAAATTAAGGAGGTTGAAAA
GGAACTTAATTTAATATTCCCAAGAGAGTTAGTCAACTTTCTTAATGAGATTGGTTACGGTTTTATTAAAGGGTCAGAGT
ATAATATTAATCGTATTATGGACCCTTACTCAATAAGAGATTTCCGTTTAAGAGTTAATGATTTTGAGTTCTATCCTGAC
ATTGAAATATATGATGCATTTGAAAATGATAAACTAATATTTTTTGAAGGTAGTGAATCAGCTTTAATGTCTATAGAATT
AAATAAAAGCGACACGAATCCAATTTATTATTATGACATTAAAATTGCAGACTCTCTTAAAGAGTTTTTAAGTAAGATAG
AAATTAATGATCAATATTACTTAGATTTAATTACAGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|