Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | paaR-paaA-parE/- |
| Location | 2950352..2950823 | Replicon | chromosome |
| Accession | NZ_CP097360 | ||
| Organism | Escherichia coli strain AGR4587 | ||
Toxin (Protein)
| Gene name | parE_1 | Uniprot ID | A0A0D7C2L1 |
| Locus tag | M7749_RS14510 | Protein ID | WP_001303511.1 |
| Coordinates | 2950545..2950823 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | paaA | Uniprot ID | Q8XAD5 |
| Locus tag | M7749_RS14505 | Protein ID | WP_001302048.1 |
| Coordinates | 2950352..2950543 (+) | Length | 64 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M7749_RS14435 (2945419) | 2945419..2945586 | - | 168 | WP_000207997.1 | hypothetical protein | - |
| M7749_RS14440 (2945597) | 2945597..2945860 | - | 264 | WP_000224216.1 | hypothetical protein | - |
| M7749_RS14445 (2945862) | 2945862..2946080 | - | 219 | WP_001142588.1 | DUF4014 family protein | - |
| M7749_RS14450 (2946082) | 2946082..2946297 | - | 216 | WP_000510387.1 | hypothetical protein | - |
| M7749_RS14455 (2946298) | 2946298..2946657 | - | 360 | WP_001289986.1 | hypothetical protein | - |
| M7749_RS14460 (2946654) | 2946654..2946830 | - | 177 | WP_021534704.1 | hypothetical protein | - |
| M7749_RS14465 (2946823) | 2946823..2947005 | - | 183 | WP_001224665.1 | hypothetical protein | - |
| M7749_RS14470 (2947134) | 2947134..2947445 | - | 312 | WP_021534703.1 | hypothetical protein | - |
| M7749_RS14475 (2947438) | 2947438..2947692 | - | 255 | WP_000004322.1 | hypothetical protein | - |
| M7749_RS14480 (2947689) | 2947689..2948111 | - | 423 | WP_021534702.1 | DUF977 family protein | - |
| M7749_RS14485 (2948152) | 2948152..2949114 | - | 963 | WP_000095673.1 | helix-turn-helix domain-containing protein | - |
| M7749_RS14490 (2949137) | 2949137..2949562 | - | 426 | WP_000693943.1 | toxin YdaT family protein | - |
| M7749_RS14495 (2949559) | 2949559..2949861 | - | 303 | WP_000172738.1 | transcriptional regulator | - |
| M7749_RS14500 (2949960) | 2949960..2950331 | + | 372 | WP_001169687.1 | hypothetical protein | - |
| M7749_RS14505 (2950352) | 2950352..2950543 | + | 192 | WP_001302048.1 | hypothetical protein | Antitoxin |
| M7749_RS14510 (2950545) | 2950545..2950823 | + | 279 | WP_001303511.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| M7749_RS14515 (2951115) | 2951115..2951267 | + | 153 | WP_000380313.1 | DUF1391 family protein | - |
| M7749_RS14520 (2951279) | 2951279..2951617 | + | 339 | WP_000394541.1 | hypothetical protein | - |
| M7749_RS14525 (2951606) | 2951606..2951800 | - | 195 | WP_001295058.1 | hypothetical protein | - |
| M7749_RS14530 (2952367) | 2952367..2952555 | + | 189 | WP_000449172.1 | cell division inhibition protein DicB | - |
| M7749_RS14535 (2952552) | 2952552..2952740 | + | 189 | WP_000199480.1 | DUF1482 family protein | - |
| M7749_RS14540 (2952836) | 2952836..2955307 | + | 2472 | WP_032284123.1 | exonuclease | - |
| M7749_RS14545 (2955369) | 2955369..2955638 | + | 270 | WP_000003742.1 | excisionase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2932125..2960033 | 27908 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|