Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 3449312..3450084 Replicon chromosome
Accession NZ_CP097127
Organism Conexibacter sp. S30A1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag M3M54_RS16610 Protein ID WP_249020130.1
Coordinates 3449584..3450084 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag M3M54_RS16605 Protein ID WP_256465800.1
Coordinates 3449312..3449587 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M54_RS16565 3444365..3445150 - 786 WP_249020122.1 LLM class F420-dependent oxidoreductase -
M3M54_RS16570 3445202..3445906 - 705 WP_249020123.1 hypothetical protein -
M3M54_RS16580 3446466..3447059 - 594 WP_249020124.1 TetR/AcrR family transcriptional regulator -
M3M54_RS16585 3447670..3448053 + 384 WP_249020125.1 hypothetical protein -
M3M54_RS16590 3448050..3448424 + 375 WP_249020126.1 transcriptional regulator -
M3M54_RS16595 3448574..3448864 - 291 WP_249020127.1 hypothetical protein -
M3M54_RS16600 3448880..3449098 - 219 WP_249020128.1 hypothetical protein -
M3M54_RS16605 3449312..3449587 + 276 WP_256465800.1 DUF1778 domain-containing protein Antitoxin
M3M54_RS16610 3449584..3450084 + 501 WP_249020130.1 GNAT family N-acetyltransferase Toxin
M3M54_RS16615 3450197..3450670 - 474 WP_249020131.1 hypothetical protein -
M3M54_RS16620 3451177..3451362 - 186 WP_249020132.1 hypothetical protein -
M3M54_RS16625 3451563..3451952 + 390 WP_249020133.1 VOC family protein -
M3M54_RS16630 3452098..3452469 - 372 WP_249020134.1 PIN domain-containing protein -
M3M54_RS16635 3452466..3453815 - 1350 WP_249019411.1 transposase -
M3M54_RS16640 3454044..3454289 - 246 WP_249020135.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
M3M54_RS16645 3454430..3454681 - 252 WP_249020136.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-148)

Antitoxin

Vibrio phage ICP1, Orf50

(9-83)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18211.88 Da        Isoelectric Point: 10.0108

>T244815 WP_249020130.1 NZ_CP097127:3449584-3450084 [Conexibacter sp. S30A1]
VSGLSLVPLSAGQDLSGFECGNPELDRWLIDHAMASQKADLARTYLVTSADAVAGYVSLTTGSIRPEAAPRRYARGMPRY
PIPTILIARLAIDRRYHRQGLGSRLLAEALRLAVAASDTAAARLVVVDAIDQQAAAFYRRWGFIDVPENPHRLFRKISDI
RTSLPQ

Download         Length: 501 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9700.93 Da        Isoelectric Point: 5.6865

>AT244815 WP_256465800.1 NZ_CP097127:3449312-3449587 [Conexibacter sp. S30A1]
MATGTRSRRIDVRVTHEQDAIIREAAAASGQTVSAFLLSAAEGRARSVLDERRHLVMSDRGFAAFAAALDEPGERVPALD
ELLGLPPISST

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References