Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2167204..2167763 Replicon chromosome
Accession NZ_CP097127
Organism Conexibacter sp. S30A1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M3M54_RS10600 Protein ID WP_249021770.1
Coordinates 2167204..2167446 (-) Length 81 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M3M54_RS10605 Protein ID WP_249019016.1
Coordinates 2167473..2167763 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M54_RS10580 2162654..2163655 - 1002 WP_249019012.1 non-homologous end-joining DNA ligase -
M3M54_RS10585 2163693..2164718 + 1026 WP_249019013.1 glycerate kinase -
M3M54_RS10590 2164958..2166208 + 1251 WP_249019014.1 ATP-binding protein -
M3M54_RS10595 2166563..2166703 + 141 WP_249019015.1 hypothetical protein -
M3M54_RS10600 2167204..2167446 - 243 WP_249021770.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M3M54_RS10605 2167473..2167763 - 291 WP_249019016.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M3M54_RS10610 2168296..2168580 + 285 WP_249019017.1 DUF1778 domain-containing protein -
M3M54_RS10615 2168577..2169080 + 504 WP_249019018.1 hypothetical protein -
M3M54_RS10620 2169279..2170676 - 1398 WP_249019019.1 glutamate decarboxylase -
M3M54_RS10625 2170676..2171035 - 360 WP_249019020.1 hypothetical protein -
M3M54_RS10630 2171032..2172591 - 1560 WP_249019021.1 type IV secretory system conjugative DNA transfer family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-77)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-73)


Sequences

Toxin        


Download         Length: 81 a.a.        Molecular weight: 9375.85 Da        Isoelectric Point: 11.1310

>T244811 WP_249021770.1 NZ_CP097127:c2167446-2167204 [Conexibacter sp. S30A1]
MPPARREFDRLPISVAAAVLETLDAIAENPRRLGKPLMFEHQGRFSARRGPYRIIYELDEPQHLVRVVAIGHRRDVYRQR

Download         Length: 243 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10199.52 Da        Isoelectric Point: 4.6182

>AT244811 WP_249019016.1 NZ_CP097127:c2167763-2167473 [Conexibacter sp. S30A1]
MAETMSLASAKARFSELVARVERQQDRVIVTRNGKPAAVVISVDDLESLEETLAVMSDAGLVAQIQESLSTAAAGDAGVG
LDDLRADLQSRRATKR

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References