Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK(toxin)
Location 1525223..1525806 Replicon chromosome
Accession NZ_CP097127
Organism Conexibacter sp. S30A1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag M3M54_RS07630 Protein ID WP_249021573.1
Coordinates 1525223..1525573 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag M3M54_RS07635 Protein ID WP_249021574.1
Coordinates 1525570..1525806 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M3M54_RS07595 1520343..1520726 - 384 WP_249021567.1 transposase -
M3M54_RS07600 1520713..1521048 - 336 Protein_1489 transposase -
M3M54_RS07605 1521634..1521882 + 249 WP_249021568.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
M3M54_RS07610 1521879..1522271 + 393 WP_256465843.1 PIN domain-containing protein -
M3M54_RS07615 1522890..1523291 + 402 WP_249021570.1 hypothetical protein -
M3M54_RS07620 1523373..1523954 + 582 WP_249021571.1 DUF6431 domain-containing protein -
M3M54_RS07625 1524146..1524487 + 342 WP_249021572.1 hypothetical protein -
M3M54_RS07630 1525223..1525573 - 351 WP_249021573.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
M3M54_RS07635 1525570..1525806 - 237 WP_249021574.1 ribbon-helix-helix protein, CopG family Antitoxin
M3M54_RS07640 1526512..1529946 - 3435 WP_249021575.1 bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-38)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12274.19 Da        Isoelectric Point: 8.7502

>T244808 WP_249021573.1 NZ_CP097127:c1525573-1525223 [Conexibacter sp. S30A1]
VIARGEVWWGDLGLPRGSAPALRRPVLVISADQYNRSRLQTVTVAIITTTQKLAGLPGNVIIPAAVSGLTEDSVLNVTQI
ATLDRGALEERIGTVPDWLLAQVDAGLARALGLTRP

Download         Length: 351 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8445.33 Da        Isoelectric Point: 4.5580

>AT244808 WP_249021574.1 NZ_CP097127:c1525806-1525570 [Conexibacter sp. S30A1]
VKTAISVPDETFDRVERAAAQLGVSRSEFFARAAERWLHDLDDPQTTDAIDRALAGIVQDTAFTDAAAAAVAKREART

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References