Detailed information of TA system TA024442

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 1521259..1521812
• Replicon: chromosome
• Accession: NC_013512
• Organism: Sulfurospirillum deleyianum DSM 6946

Toxin (Protein)

• Gene name: relE
• Uniprot ID: D1B342
• Locus tag: SDEL_RS07555
• Protein ID: WP_012857263.1
• Coordinates: 1521259..1521555 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: D1B343
• Locus tag: SDEL_RS07560
• Protein ID: WP_012857264.1
• Coordinates: 1521555..1521812 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SDEL_RS07540	1517433..1519370	-	1938	WP_012857260.1	sulfatase-like hydrolase/transferase	-
SDEL_RS07545	1519540..1520856	+	1317	WP_012857261.1	ammonium transporter	-
SDEL_RS07550	1520871..1521209	+	339	WP_012857262.1	P-II family nitrogen regulator	-
SDEL_RS07555	1521259..1521555	-	297	WP_012857263.1	type II toxin-antitoxin system YafQ family toxin	Toxin
SDEL_RS07560	1521555..1521812	-	258	WP_012857264.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
SDEL_RS07565	1522185..1522730	-	546	WP_012857265.1	type II toxin-antitoxin system VapC family toxin	-
SDEL_RS07570	1522720..1523079	-	360	WP_012857266.1	STAS-like domain-containing protein	-
SDEL_RS07575	1523089..1523907	-	819	WP_190275677.1	ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-94)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-84)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11815.64 Da
• Isoelectric Point: 8.8800

>T24442 WP_012857263.1 NC_013512:c1521555-1521259 [Sulfurospirillum deleyianum DSM 6946]
MYTPEYHRFFKKDIERDKKSGQFSIEDFTLLKEVMSVLLSGEVLHEKHQNHLLKGEWDGTYECHIKNDWLLIYRLDVSNR
AIIFVRLGTHSQLFKKFK

Nucleotide

• Length: 297 bp

>T24442 NC_013512:c1521555-1521259 [Sulfurospirillum deleyianum DSM 6946]
ATGTACACCCCAGAGTATCACCGCTTCTTTAAAAAAGATATTGAACGTGATAAAAAGAGTGGGCAATTTTCAATCGAGGA
TTTTACGCTTTTAAAAGAGGTAATGTCTGTACTGCTTAGCGGTGAGGTGTTGCATGAAAAACACCAAAATCACCTTTTAA
AAGGGGAGTGGGATGGAACGTATGAATGTCATATTAAAAACGATTGGCTTTTGATTTATCGACTTGATGTTTCAAATAGA
GCCATCATTTTTGTAAGGCTAGGAACGCACTCCCAACTCTTTAAAAAATTTAAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9441.88 Da
• Isoelectric Point: 6.7257

>AT24442 WP_012857264.1 NC_013512:c1521812-1521555 [Sulfurospirillum deleyianum DSM 6946]
MTGTAMTVRIDPEIKNKAAEYLKQMGLTTSEATRLFLHSVVLHKGLPFELKIPNEETATAIQESKEGKNVIKHTSSKELF
DDLGL

Nucleotide

• Length: 258 bp

>AT24442 NC_013512:c1521812-1521555 [Sulfurospirillum deleyianum DSM 6946]
ATGACAGGAACAGCGATGACTGTACGTATTGACCCTGAAATTAAAAACAAAGCAGCAGAGTATCTTAAACAAATGGGCTT
AACCACCAGTGAAGCCACACGACTCTTTTTACACAGCGTAGTCCTTCACAAAGGGCTTCCTTTTGAGCTCAAAATCCCTA
ACGAAGAGACAGCGACAGCTATCCAAGAGTCCAAAGAGGGTAAAAATGTCATTAAACACACCTCTTCAAAAGAACTGTTT
GATGATTTAGGGTTGTAA

Structures

Toxin

• AlphaFold DB: D1B342

Antitoxin

• AlphaFold DB: D1B343