Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ldrD-symR/Ldr(toxin) |
| Location | 204941..205162 | Replicon | chromosome |
| Accession | NZ_CP096837 | ||
| Organism | Escherichia coli strain PS10-3 | ||
Toxin (Protein)
| Gene name | ldrD | Uniprot ID | S1NWX0 |
| Locus tag | MYF74_RS00910 | Protein ID | WP_001295224.1 |
| Coordinates | 205055..205162 (+) | Length | 36 a.a. |
Antitoxin (RNA)
| Gene name | symR | ||
| Locus tag | - | ||
| Coordinates | 204941..205006 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MYF74_RS00885 (200825) | 200825..201829 | + | 1005 | WP_000107036.1 | dipeptide ABC transporter ATP-binding subunit DppF | - |
| MYF74_RS00890 (201859) | 201859..203130 | - | 1272 | WP_001308130.1 | aromatic amino acid transport family protein | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_13 | - | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_13 | - | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_13 | - | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_13 | - | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_21 | - | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_21 | - | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_21 | - | - |
| - (203492) | 203492..203557 | - | 66 | NuclAT_21 | - | - |
| MYF74_RS00895 (203606) | 203606..203713 | + | 108 | WP_072193518.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_15 | - | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_15 | - | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_15 | - | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_15 | - | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_23 | - | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_23 | - | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_23 | - | - |
| - (203975) | 203975..204031 | - | 57 | NuclAT_23 | - | - |
| MYF74_RS00900 (204089) | 204089..204196 | + | 108 | WP_077628235.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_14 | - | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_14 | - | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_14 | - | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_14 | - | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_22 | - | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_22 | - | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_22 | - | - |
| - (204458) | 204458..204523 | - | 66 | NuclAT_22 | - | - |
| MYF74_RS00905 (204572) | 204572..204679 | + | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
| - (204941) | 204941..205006 | - | 66 | NuclAT_12 | - | Antitoxin |
| - (204941) | 204941..205006 | - | 66 | NuclAT_12 | - | Antitoxin |
| - (204941) | 204941..205006 | - | 66 | NuclAT_12 | - | Antitoxin |
| - (204941) | 204941..205006 | - | 66 | NuclAT_12 | - | Antitoxin |
| - (204941) | 204941..205006 | - | 66 | NuclAT_20 | - | Antitoxin |
| - (204941) | 204941..205006 | - | 66 | NuclAT_20 | - | Antitoxin |
| - (204941) | 204941..205006 | - | 66 | NuclAT_20 | - | Antitoxin |
| - (204941) | 204941..205006 | - | 66 | NuclAT_20 | - | Antitoxin |
| MYF74_RS00910 (205055) | 205055..205162 | + | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
| MYF74_RS00915 (205249) | 205249..206928 | - | 1680 | WP_000191579.1 | cellulose biosynthesis protein BcsG | - |
| MYF74_RS00920 (206925) | 206925..207116 | - | 192 | WP_000988308.1 | cellulose biosynthesis protein BcsF | - |
| MYF74_RS00925 (207113) | 207113..208684 | - | 1572 | WP_001204920.1 | cellulose biosynthesis c-di-GMP-binding protein BcsE | - |
| MYF74_RS00930 (208957) | 208957..209145 | + | 189 | WP_001063314.1 | cellulose biosynthesis protein BcsR | - |
| MYF74_RS00935 (209157) | 209157..209909 | + | 753 | WP_000279541.1 | cellulose biosynthesis protein BcsQ | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3882.70 Da Isoelectric Point: 9.0157
>T243472 WP_001295224.1 NZ_CP096837:205055-205162 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK
Download Length: 108 bp
>T243472 NZ_OX352324:c5783082-5782855 [Pseudomonas sp. MM221]
ATGCGCAGTCGTGAAGTTATCCAGCTTATCGAAGCTGACGGTTGGTACGAGGTCGATGTAAAAGGCAGCCATCACCAATT
CAGGCACCCCACAAAAAGGGGGCGAGTTAAGTTTCCTCATCCCAAGAGCGAGCTGCCCAAAGGTACAGTACGCAGCATTC
TGAAACAGGCCGGTTTGATTCAGACCGGTGGCGTTGCCAGCACGAGTGTCAACGGAGGTGATCAATGA
ATGCGCAGTCGTGAAGTTATCCAGCTTATCGAAGCTGACGGTTGGTACGAGGTCGATGTAAAAGGCAGCCATCACCAATT
CAGGCACCCCACAAAAAGGGGGCGAGTTAAGTTTCCTCATCCCAAGAGCGAGCTGCCCAAAGGTACAGTACGCAGCATTC
TGAAACAGGCCGGTTTGATTCAGACCGGTGGCGTTGCCAGCACGAGTGTCAACGGAGGTGATCAATGA
Antitoxin
Download Length: 66 bp
>AT243472 NZ_CP096837:c205006-204941 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
