Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 51992..52263 Replicon chromosome
Accession NZ_CP096834
Organism Escherichia coli strain PM4-5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 52122..52225 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 51992..52263 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYF75_RS01900 48547..49209 - 663 WP_000944256.1 exodeoxyribonuclease X -
MYF75_RS01905 49233..49889 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
MYF75_RS01910 49991..50221 - 231 WP_000916763.1 DNA polymerase III subunit theta -
MYF75_RS01915 50360..50734 + 375 WP_000204700.1 CopC domain-containing protein YobA -
MYF75_RS01920 50738..51610 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
MYF75_RS01925 51623..51964 + 342 WP_000976472.1 YebY family protein -
- 51992..52263 - 272 - - Antitoxin
- 52122..52225 + 104 - - Toxin
MYF75_RS01930 52360..53016 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
MYF75_RS01935 53017..53208 - 192 WP_001296140.1 YebW family protein -
MYF75_RS01940 53313..53549 - 237 WP_001295499.1 YebV family protein -
MYF75_RS01945 53667..55106 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1..68102 68101


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T243437 NZ_CP096834:52122-52225 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT243437 NZ_CP096834:c52263-51992 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References