Detailed information of TA system TA243212

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2563803..2564129
• Replicon: chromosome
• Accession: NZ_CP096590
• Organism: Bacillus rugosus strain A78.1

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M0696_RS12950
• Protein ID: WP_024122157.1
• Coordinates: 2563803..2563982 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2563906..2564129 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M0696_RS12940 (2563029)	2563029..2563166	-	138	WP_021480099.1	hypothetical protein	-
M0696_RS12945 (2563208)	2563208..2563657	-	450	WP_248602019.1	phage portal protein	-
M0696_RS12950 (2563803)	2563803..2563982	+	180	WP_024122157.1	type I toxin-antitoxin system toxin TxpA	Toxin
- (2563906)	2563906..2564129	-	224	NuclAT_0	-	Antitoxin
- (2563906)	2563906..2564129	-	224	NuclAT_0	-	Antitoxin
- (2563906)	2563906..2564129	-	224	NuclAT_0	-	Antitoxin
- (2563906)	2563906..2564129	-	224	NuclAT_0	-	Antitoxin
M0696_RS12955 (2564365)	2564365..2564454	+	90	WP_074794433.1	type I toxin-antitoxin system toxin BsrH	-
M0696_RS12960 (2564855)	2564855..2565298	-	444	WP_019715091.1	phage tail tube protein	-
M0696_RS12965 (2565301)	2565301..2566701	-	1401	WP_248602020.1	phage tail sheath family protein	-
M0696_RS12970 (2566702)	2566702..2566893	-	192	WP_248602021.1	hypothetical protein	-
M0696_RS12975 (2566890)	2566890..2567327	-	438	WP_248602022.1	phage portal protein	-
M0696_RS12980 (2567340)	2567340..2567843	-	504	WP_248602023.1	HK97 gp10 family phage protein	-
M0696_RS12985 (2567840)	2567840..2568202	-	363	WP_248602024.1	YqbH/XkdH family protein	-
M0696_RS12990 (2568199)	2568199..2568594	-	396	WP_075748306.1	DUF3199 family protein	-
M0696_RS12995 (2568599)	2568599..2568910	-	312	WP_248602025.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	aadK	-	2536649..2594719	58070

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T243212 WP_024122157.1 NZ_CP096590:2563803-2563982 [Bacillus rugosus]
MSTYESLMVMIGFANLIGGIMTWVLSLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T243212 NZ_OW970436:c4770968-4770684 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCAGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin

Nucleotide

• Length: 224 bp

>AT243212 NZ_CP096590:c2564129-2563906 [Bacillus rugosus]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTGATAGTTGGTACCACATTACCACAATACAACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCATAAAATATAAAAGCCAGAGTGTTGCAGCACTCTAGCTTTTAAAGAAGAAACTACCCTTTAATA
GGAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Antitoxin