Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2582139..2582373 | Replicon | chromosome |
| Accession | NC_013361 | ||
| Organism | Escherichia coli O26:H11 str. 11368 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2582140..2582243 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2582139..2582373 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECO26_RS13905 | 2579338..2580147 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| ECO26_RS32150 | 2580204..2580398 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| ECO26_RS13910 | 2580391..2580579 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2580397..2580575 | - | 179 | NuclAT_1 | - | - |
| - | 2580397..2580575 | - | 179 | NuclAT_1 | - | - |
| - | 2580397..2580575 | - | 179 | NuclAT_1 | - | - |
| - | 2580397..2580575 | - | 179 | NuclAT_1 | - | - |
| ECO26_RS32155 | 2580686..2580967 | + | 282 | WP_001443927.1 | excisionase | - |
| ECO26_RS13915 | 2580933..2582048 | + | 1116 | WP_001189089.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2582139..2582373 | + | 235 | - | - | Antitoxin |
| - | 2582140..2582243 | - | 104 | - | - | Toxin |
| ECO26_RS13925 | 2582401..2582742 | - | 342 | WP_000976492.1 | YebY family protein | - |
| ECO26_RS13930 | 2582755..2583627 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| ECO26_RS13935 | 2583631..2584005 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| ECO26_RS13940 | 2584144..2584374 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| ECO26_RS13945 | 2584476..2585132 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| ECO26_RS13950 | 2585156..2585818 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2524506..2587875 | 63369 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T24320 NC_013361:c2582243-2582140 [Escherichia coli O26:H11 str. 11368]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT24320 NC_013361:2582139-2582373 [Escherichia coli O26:H11 str. 11368]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
