Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071329..2071474 Replicon chromosome
Accession NZ_CP096238
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD02201

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2071365..2071467 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071329..2071474 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0536_RS09935 2066459..2068519 + 2061 WP_004151449.1 oligopeptidase B -
M0536_RS09940 2068523..2069182 - 660 WP_002911407.1 exodeoxyribonuclease X -
M0536_RS09945 2069261..2069491 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M0536_RS09950 2069604..2069978 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M0536_RS09955 2069982..2070851 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
M0536_RS09960 2070868..2071206 + 339 WP_002911404.1 YebY family protein -
- 2071329..2071474 - 146 - - Antitoxin
- 2071365..2071467 + 103 - - Toxin
M0536_RS09965 2071842..2071985 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M0536_RS09970 2072090..2073058 - 969 WP_014907334.1 VirK/YbjX family protein -
M0536_RS09975 2073215..2073868 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M0536_RS09980 2073865..2074056 - 192 WP_002911395.1 YebW family protein -
M0536_RS09985 2074154..2074393 - 240 WP_002911393.1 YebV family protein -
M0536_RS09990 2074509..2075942 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T242939 NZ_CP096238:2071365-2071467 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT242939 NZ_CP096238:c2071474-2071329 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References