Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1207441..1208110 Replicon chromosome
Accession NZ_CP096169
Organism Shewanella sp. JNE2

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag MZ182_RS05475 Protein ID WP_041420529.1
Coordinates 1207670..1208110 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag MZ182_RS05470 Protein ID WP_014610118.1
Coordinates 1207441..1207689 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZ182_RS05445 (MZ182_05445) 1203064..1203870 + 807 WP_011790288.1 prolipoprotein diacylglyceryl transferase -
MZ182_RS05450 (MZ182_05450) 1203870..1204664 + 795 WP_011790287.1 thymidylate synthase -
MZ182_RS05455 (MZ182_05455) 1204781..1205956 + 1176 WP_011918885.1 Na+/H+ antiporter NhaA -
MZ182_RS05460 (MZ182_05460) 1205953..1206339 + 387 WP_011790285.1 hypothetical protein -
MZ182_RS05465 (MZ182_05465) 1206447..1207355 + 909 WP_011790284.1 transcriptional activator NhaR -
MZ182_RS05470 (MZ182_05470) 1207441..1207689 + 249 WP_014610118.1 succinate dehydrogenase assembly factor 2 Antitoxin
MZ182_RS05475 (MZ182_05475) 1207670..1208110 + 441 WP_041420529.1 hypothetical protein Toxin
MZ182_RS05480 (MZ182_05480) 1208147..1209760 - 1614 WP_248065600.1 L-aspartate oxidase -
MZ182_RS05485 (MZ182_05485) 1209950..1210528 + 579 WP_011790280.1 RNA polymerase sigma factor RpoE -
MZ182_RS05490 (MZ182_05490) 1210555..1211175 + 621 WP_248065601.1 anti sigma-E factor RseA C-terminal domain-containing protein -
MZ182_RS05495 (MZ182_05495) 1211188..1212120 + 933 WP_011790278.1 MucB/RseB C-terminal domain-containing protein -
MZ182_RS05500 (MZ182_05500) 1212131..1212604 + 474 WP_011918888.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(6-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-78)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17327.51 Da        Isoelectric Point: 8.8774

>T242812 WP_041420529.1 NZ_CP096169:1207670-1208110 [Shewanella sp. JNE2]
VEEQHHSFSVKASFDQRLSLVVFMCVCSSSFLIWPYTEHWLVALLRLGLFLLSVSFLIWQLWRLKDWRLSFMLNGKGDGR
LSTGEHFRILRRTWVTPFVCMIYIDVEENTRLVLLWADMFTGVDYRHLCRLLLKAKMLQAKSQVEI

Download         Length: 441 bp

>T242812 NZ_OW967795:3341277-3341495 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9545.15 Da        Isoelectric Point: 4.5994

>AT242812 WP_014610118.1 NZ_CP096169:1207441-1207689 [Shewanella sp. JNE2]
MELMNIARVRWACRRGMLELDVLFQPFVENIYQDLSDIDKASFIRLLECEDPELFAWFMGHEACPDAELARMVVKVRGRA
AP

Download         Length: 249 bp

>AT242812 NZ_OW967795:3340877-3341251 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References