Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2075917..2076062 Replicon chromosome
Accession NZ_CP095421
Organism Klebsiella pneumoniae strain IM057

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2075953..2076055 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2075917..2076062 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MWR70_RS10255 (MWR70_10240) 2071047..2073107 + 2061 WP_004151449.1 oligopeptidase B -
MWR70_RS10260 (MWR70_10245) 2073111..2073770 - 660 WP_002911407.1 exodeoxyribonuclease X -
MWR70_RS10265 (MWR70_10250) 2073849..2074079 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MWR70_RS10270 (MWR70_10255) 2074192..2074566 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MWR70_RS10275 (MWR70_10260) 2074570..2075439 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
MWR70_RS10280 (MWR70_10265) 2075456..2075794 + 339 WP_002911404.1 YebY family protein -
- 2075917..2076062 - 146 - - Antitoxin
- 2075953..2076055 + 103 - - Toxin
MWR70_RS10285 (MWR70_10270) 2076430..2076573 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MWR70_RS10290 (MWR70_10275) 2076678..2077646 - 969 WP_004151446.1 VirK/YbjX family protein -
MWR70_RS10295 (MWR70_10280) 2077803..2078456 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MWR70_RS10300 (MWR70_10285) 2078453..2078644 - 192 WP_002911395.1 YebW family protein -
MWR70_RS10305 (MWR70_10290) 2078742..2078981 - 240 WP_002911393.1 YebV family protein -
MWR70_RS10310 (MWR70_10295) 2079097..2080530 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T241924 NZ_CP095421:2075953-2076055 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT241924 NZ_CP095421:c2076062-2075917 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References