Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2065296..2065442 Replicon chromosome
Accession NZ_CP094272
Organism Klebsiella aerogenes strain NY1688

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2065331..2065434 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2065296..2065442 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQE04_RS10055 (MQE04_10055) 2060405..2062465 + 2061 WP_224146945.1 oligopeptidase B -
MQE04_RS10060 (MQE04_10060) 2062468..2063127 - 660 WP_015366006.1 exodeoxyribonuclease X -
MQE04_RS10065 (MQE04_10065) 2063207..2063437 - 231 WP_224146944.1 DNA polymerase III subunit theta -
MQE04_RS10070 (MQE04_10070) 2063572..2063946 + 375 WP_047063540.1 CopC domain-containing protein YobA -
MQE04_RS10075 (MQE04_10075) 2063950..2064819 + 870 WP_224146943.1 copper homeostasis membrane protein CopD -
MQE04_RS10080 (MQE04_10080) 2064833..2065174 + 342 WP_015705946.1 YebY family protein -
- 2065296..2065442 - 147 - - Antitoxin
- 2065331..2065434 + 104 - - Toxin
MQE04_RS10085 (MQE04_10085) 2065562..2066515 - 954 WP_026612269.1 spore coat U domain-containing protein -
MQE04_RS10090 (MQE04_10090) 2066528..2068852 - 2325 WP_048228936.1 fimbria/pilus outer membrane usher protein -
MQE04_RS10095 (MQE04_10095) 2068855..2069604 - 750 WP_015366013.1 molecular chaperone -
MQE04_RS10100 (MQE04_10100) 2069622..2070140 - 519 WP_045411482.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T239427 NZ_CP094272:2065331-2065434 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 147 bp

>AT239427 NZ_CP094272:c2065442-2065296 [Klebsiella aerogenes]
TAATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAA
GTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References