Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 580288..580912 Replicon chromosome
Accession NZ_CP094128
Organism Helicobacter pylori strain Hpfe055

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG79_RS02805 Protein ID WP_245107764.1
Coordinates 580646..580912 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG79_RS02800 Protein ID WP_245107763.1
Coordinates 580288..580665 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG79_RS02775 (MPG79_02775) 575537..576649 + 1113 WP_245107760.1 hydrogenase formation protein HypD -
MPG79_RS02780 (MPG79_02780) 576600..577121 - 522 WP_245107761.1 hypothetical protein -
MPG79_RS02795 (MPG79_02795) 577642..579867 + 2226 WP_245107762.1 Hop family adhesin BabA -
MPG79_RS02800 (MPG79_02800) 580288..580665 + 378 WP_245107763.1 hypothetical protein Antitoxin
MPG79_RS02805 (MPG79_02805) 580646..580912 + 267 WP_245107764.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG79_RS02810 (MPG79_02810) 581017..581541 - 525 WP_245107765.1 acyl-CoA thioesterase -
MPG79_RS02815 (MPG79_02815) 581682..582524 + 843 WP_245107766.1 SDR family oxidoreductase -
MPG79_RS02820 (MPG79_02820) 582517..583497 + 981 WP_180582038.1 iron ABC transporter permease -
MPG79_RS02825 (MPG79_02825) 583497..584264 + 768 WP_245107767.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10376.22 Da        Isoelectric Point: 9.0167

>T239254 WP_245107764.1 NZ_CP094128:580646-580912 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILTLRKKEPLDPQFKDHALKGKWKPFRECHIKTDILLVYLVRDDELILVR
LGSHSELF

Download         Length: 267 bp

>T239254 NZ_LR890651:2833629-2833736 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14730.76 Da        Isoelectric Point: 9.0052

>AT239254 WP_245107763.1 NZ_CP094128:580288-580665 [Helicobacter pylori]
MPNTTAKKDYTQYSEKQLFNLIHQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNKLLQKISQAFDDKRDCCL
GRKIPNLETQQAMRDALNKETDLIVEDFSSYSDERKRALGVETQP

Download         Length: 378 bp

>AT239254 NZ_LR890651:c2833582-2833516 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References