Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1955402..1955547 Replicon chromosome
Accession NZ_CP093495
Organism Klebsiella pneumoniae strain VA32

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1955438..1955540 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1955402..1955547 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO414_RS09500 (MO414_09490) 1950532..1952592 + 2061 WP_004151449.1 oligopeptidase B -
MO414_RS09505 (MO414_09495) 1952596..1953255 - 660 WP_032425085.1 exodeoxyribonuclease X -
MO414_RS09510 (MO414_09500) 1953334..1953564 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MO414_RS09515 (MO414_09505) 1953677..1954051 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MO414_RS09520 (MO414_09510) 1954055..1954924 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MO414_RS09525 (MO414_09515) 1954941..1955279 + 339 WP_016529031.1 YebY family protein -
- 1955402..1955547 - 146 - - Antitoxin
- 1955438..1955540 + 103 - - Toxin
MO414_RS09530 (MO414_09520) 1955915..1956058 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MO414_RS09535 (MO414_09525) 1956163..1957131 - 969 WP_004151446.1 VirK/YbjX family protein -
MO414_RS09540 (MO414_09530) 1957288..1957941 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MO414_RS09545 (MO414_09535) 1957938..1958129 - 192 WP_002911395.1 YebW family protein -
MO414_RS09550 (MO414_09540) 1958227..1958466 - 240 WP_002911393.1 YebV family protein -
MO414_RS09555 (MO414_09545) 1958582..1960015 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238778 NZ_CP093495:1955438-1955540 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238778 NZ_CP093495:c1955547-1955402 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References