237954

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3129974..3130448 Replicon chromosome
Accession NZ_CP093260
Organism Moellerella wisconsensis strain W17-3

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag MNY68_RS13760 Protein ID WP_241540606.1
Coordinates 3129974..3130240 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag MNY68_RS13765 Protein ID WP_047257105.1
Coordinates 3130224..3130448 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY68_RS13740 (MNY68_13740) 3125293..3126207 - 915 WP_047257110.1 ribonuclease Z -
MNY68_RS13745 (MNY68_13745) 3126237..3127838 - 1602 WP_241540605.1 RNA repair transcriptional activator RtcR -
MNY68_RS13750 (MNY68_13750) 3128122..3128337 + 216 WP_047257108.1 hypothetical protein -
MNY68_RS13755 (MNY68_13755) 3128359..3129486 + 1128 WP_047257107.1 slipin family protein -
MNY68_RS13760 (MNY68_13760) 3129974..3130240 - 267 WP_241540606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNY68_RS13765 (MNY68_13765) 3130224..3130448 - 225 WP_047257105.1 TraY domain-containing protein Antitoxin
MNY68_RS16345 3130638..3130766 + 129 WP_269430907.1 hypothetical protein -
MNY68_RS13770 (MNY68_13770) 3130915..3131292 - 378 WP_241501090.1 hypothetical protein -
MNY68_RS13775 (MNY68_13775) 3131289..3131609 - 321 WP_241540607.1 hypothetical protein -
MNY68_RS13780 (MNY68_13780) 3131634..3132224 - 591 WP_241540608.1 hypothetical protein -
MNY68_RS13785 (MNY68_13785) 3132632..3132850 - 219 WP_053907512.1 hypothetical protein -
MNY68_RS13790 (MNY68_13790) 3133085..3133861 - 777 WP_241540609.1 hypothetical protein -
MNY68_RS13795 (MNY68_13795) 3134064..3134282 - 219 WP_241540610.1 hypothetical protein -
MNY68_RS13800 (MNY68_13800) 3134520..3135296 - 777 WP_241540611.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-45)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10404.04 Da        Isoelectric Point: 9.5211

>T237954 WP_241540606.1 NZ_CP093260:c3130240-3129974 [Moellerella wisconsensis]
MVWTINYSERALKSLRKMDKQSARRIVDFMGLRIAALDDPRQLGKSLKGELGEFWRYRVGDYRILCEIRDDELVILAATT
GHRREIYE

Download         Length: 267 bp

>T237954 NZ_LR883014:90280-90459 [Escherichia coli]
ATGAAGTACTTGAACACTACTGATTGTAGCCTCTTCCTTGCAGAGAGGTCAAAGTTTATGACGAAATATGCCCTTATCGG
GTTGCTCGCCGTGTGTGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTTATGTGAACTGAATATTCACAGAG
GAAATTGCGTATTACCGTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8470.51 Da        Isoelectric Point: 4.5201

>AT237954 WP_047257105.1 NZ_CP093260:c3130448-3130224 [Moellerella wisconsensis]
MLAIRLSDDIETRLESLAKQTGRTKTFYAREAILTHLEDLEDYYLSAETIAKIRSGEELIHSSEEVRKTLGLDD

Download         Length: 225 bp

>AT237954 NZ_LR883014:c90288-90232 [Escherichia coli]
GTACTTCATGCAGACCTCACGAGTTAATGGATTAACAAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References