Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2959489..2960128 Replicon chromosome
Accession NZ_CP093255
Organism Moellerella wisconsensis strain W1

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag MNY70_RS13105 Protein ID WP_269430900.1
Coordinates 2959904..2960128 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag MNY70_RS13100 Protein ID WP_047256412.1
Coordinates 2959489..2959857 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY70_RS13075 (MNY70_13075) 2954690..2955451 - 762 WP_047256407.1 DNA polymerase III subunit epsilon -
MNY70_RS13080 (MNY70_13080) 2955508..2955975 + 468 WP_047256408.1 ribonuclease HI -
MNY70_RS13085 (MNY70_13085) 2955978..2956694 - 717 WP_047256409.1 methyltransferase domain-containing protein -
MNY70_RS13090 (MNY70_13090) 2956729..2957484 + 756 WP_047256410.1 hydroxyacylglutathione hydrolase -
MNY70_RS13095 (MNY70_13095) 2957556..2958911 + 1356 WP_241544637.1 murein transglycosylase D -
MNY70_RS13100 (MNY70_13100) 2959489..2959857 + 369 WP_047256412.1 Hha toxicity modulator TomB Antitoxin
MNY70_RS13105 (MNY70_13105) 2959904..2960128 + 225 WP_269430900.1 HHA domain-containing protein Toxin
MNY70_RS13115 (MNY70_13115) 2960888..2961349 - 462 WP_241544638.1 YbaY family lipoprotein -
MNY70_RS13120 (MNY70_13120) 2961746..2962609 + 864 WP_241501033.1 acyl-CoA thioesterase II -
MNY70_RS13125 (MNY70_13125) 2963674..2964957 - 1284 WP_047256416.1 ammonium transporter AmtB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(15-71)

Antitoxin

Biofilm formation regulator YbaJ

(1-117)


Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8977.32 Da        Isoelectric Point: 5.8622

>T237945 WP_269430900.1 NZ_CP093255:2959904-2960128 [Moellerella wisconsensis]
MNERQENMTKTDYLMRLRKCTTIETLERVIEKNKYELSDDELELFFSAADHRLAELTMNKLYDKIPASVWKYVR

Download         Length: 225 bp

>T237945 NZ_LR883012:2752705-2752812 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14371.20 Da        Isoelectric Point: 4.5817

>AT237945 WP_047256412.1 NZ_CP093255:2959489-2959857 [Moellerella wisconsensis]
MDEYSPRYYDTAELKYLCDSLNNDAILSLHKTKTHWINDLSSQQSTNLNELIEHVAAFFWKFKIKYPSERLVISLVDEYL
DETYNLFGSPLITLNEFSDWQKMNTHLIDELNNDLKCSVAKL

Download         Length: 369 bp

>AT237945 NZ_LR883012:c2752658-2752592 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References