Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2452854..2453511 Replicon chromosome
Accession NZ_CP093245
Organism Moellerella wisconsensis strain W51

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MNY72_RS10875 Protein ID WP_047255277.1
Coordinates 2452854..2453264 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag MNY72_RS10880 Protein ID WP_047255278.1
Coordinates 2453245..2453511 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY72_RS10855 (MNY72_10845) 2448118..2449851 - 1734 WP_241500860.1 single-stranded-DNA-specific exonuclease RecJ -
MNY72_RS10860 (MNY72_10850) 2449860..2450552 - 693 WP_047255274.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MNY72_RS10865 (MNY72_10855) 2450577..2451488 - 912 WP_047255275.1 site-specific tyrosine recombinase XerD -
MNY72_RS10870 (MNY72_10860) 2451709..2452227 + 519 WP_047255276.1 flavodoxin FldB -
MNY72_RS10875 (MNY72_10865) 2452854..2453264 - 411 WP_047255277.1 protein YgfX Toxin
MNY72_RS10880 (MNY72_10870) 2453245..2453511 - 267 WP_047255278.1 FAD assembly factor SdhE Antitoxin
MNY72_RS10885 (MNY72_10875) 2453772..2454764 + 993 WP_241500861.1 tRNA-modifying protein YgfZ -
MNY72_RS10890 (MNY72_10880) 2454782..2455402 + 621 WP_047255280.1 HD domain-containing protein -
MNY72_RS10895 (MNY72_10885) 2455574..2458453 - 2880 WP_241500863.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15525.49 Da        Isoelectric Point: 10.3270

>T237929 WP_047255277.1 NZ_CP093245:c2453264-2452854 [Moellerella wisconsensis]
VVLWKSNLSISWMAQLFSTCVHCVLGLVLLLAPWPTGNSIIWLPLLMVTIASWAKSQKNINKYKGIIVLTNGNKVQWKKN
EWSIITPPWCTRFGILLTLSALQGKPRKIKLWIAADAISEDDWRNLNQLLLQYPDI

Download         Length: 411 bp

>T237929 NZ_LR883008:c45819-45403 [Escherichia coli]
GTGAACAAGACTTATATGCTTGATACCTGTATCTGCTCGTTCATCATGCGTGAACAGCCAGAAGCCGTCCTGAAGCGTCT
GGAGCAGGCGGTGCTACGCGGCCACCGTATAGTGGTCTCGGCCATCACCTACTCTGAAATGCGCTTCGGGGCTACCGGCC
CAAAGGCCTCACCACGTCACGTCCAACTGGTCGATGAATTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCC
GCAGTAGACGCCACCACGAAGGTTAAAGTGGCACTGCGGCTGGCCGGGACGCCGATCGGCCCGAACGACACGGCGATTGC
CGGGCACGCCATCGCCGCCGGGGCGATACTGGTAACGAATAATACAAGAGAATTTGAGCGGGTGCCTGACCTGGTGCTGG
AAGACTGGGTGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10681.11 Da        Isoelectric Point: 5.1391

>AT237929 WP_047255278.1 NZ_CP093245:c2453511-2453245 [Moellerella wisconsensis]
MDIDNKARIHWACRRGMRELDISIMPFFEHEYDGLNDNEKHQFIRLLECADPDLFNWLMNHGRPDDDELYHMIKLIQQRN
KDRGPVEI

Download         Length: 267 bp

>AT237929 NZ_LR883008:c46046-45816 [Escherichia coli]
ATGAGAACCGTATCGATATTTAAAAATGGCAACAACCGCGCCATCCGTCTGCCTCGTGATCTGGATTTTGAGGGGGTGAG
CGAGCTCGAGATCGTCCGGGAAGGGGACAGCATCATCCTGCGCCCCATCCGGCCAACCTGGGGATCATTCCTAGAGTGCG
AAAAAGCCGATCCAGATTTTATGGCGGAGCGCGAGGATGTTGTCAGCGACGAAGGGCGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References