Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2164893..2165044 Replicon chromosome
Accession NZ_CP092635
Organism Enterobacter cloacae strain EFN743

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2164928..2165031 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2164893..2165044 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKZ88_RS10610 (MKZ88_10610) 2161377..2162039 - 663 WP_013096100.1 exodeoxyribonuclease X -
MKZ88_RS10615 (MKZ88_10615) 2162063..2162713 - 651 WP_058650806.1 carbon-nitrogen hydrolase family protein -
MKZ88_RS10620 (MKZ88_10620) 2162823..2163053 - 231 WP_013096102.1 DNA polymerase III subunit theta -
MKZ88_RS10625 (MKZ88_10625) 2163191..2163562 + 372 WP_058650805.1 CopC domain-containing protein YobA -
MKZ88_RS10630 (MKZ88_10630) 2163564..2164433 + 870 WP_060578714.1 copper homeostasis membrane protein CopD -
MKZ88_RS10635 (MKZ88_10635) 2164450..2164788 + 339 WP_013096105.1 YebY family protein -
- 2164893..2165044 - 152 - - Antitoxin
- 2164928..2165031 + 104 - - Toxin
MKZ88_RS10640 (MKZ88_10640) 2165195..2166136 - 942 WP_058650803.1 VirK/YbjX family protein -
MKZ88_RS10645 (MKZ88_10645) 2166303..2166947 + 645 WP_023620457.1 protein-serine/threonine phosphatase -
MKZ88_RS10650 (MKZ88_10650) 2166981..2167220 - 240 WP_013096113.1 YebV family protein -
MKZ88_RS10655 (MKZ88_10655) 2167326..2168768 - 1443 WP_058650802.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T236809 NZ_CP092635:2164928-2165031 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 152 bp

>AT236809 NZ_CP092635:c2165044-2164893 [Enterobacter cloacae]
CTTTCAATCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References