Detailed information of TA system TA235977

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrH/-
• Location: 2184967..2185184
• Replicon: chromosome
• Accession: NZ_CP092369
• Organism: Bacillus subtilis strain ZW

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: MID01_RS11145
• Protein ID: WP_109962752.1
• Coordinates: 2184967..2185143 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrH
Locus tag	-
Coordinates	2185084..2185184 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MID01_RS11100 (2180078)	2180078..2180413	-	336	WP_109962744.1	hypothetical protein	-
MID01_RS11105 (2180451)	2180451..2180747	-	297	WP_109962745.1	hypothetical protein	-
MID01_RS11110 (2180823)	2180823..2181068	-	246	WP_109962746.1	hypothetical protein	-
MID01_RS11115 (2181068)	2181068..2181268	-	201	WP_109962747.1	hypothetical protein	-
MID01_RS11120 (2181306)	2181306..2182205	-	900	WP_109962748.1	hypothetical protein	-
MID01_RS11125 (2182317)	2182317..2182748	-	432	WP_109962749.1	hypothetical protein	-
MID01_RS11130 (2183165)	2183165..2184382	-	1218	WP_109962750.1	hypothetical protein	-
MID01_RS11135 (2184464)	2184464..2184652	-	189	WP_003230987.1	hypothetical protein	-
MID01_RS11140 (2184697)	2184697..2184948	-	252	WP_109962751.1	hypothetical protein	-
MID01_RS11145 (2184967)	2184967..2185143	-	177	WP_109962752.1	hypothetical protein	Toxin
- (2185084)	2185084..2185184	+	101	NuclAT_1	-	Antitoxin
- (2185084)	2185084..2185184	+	101	NuclAT_1	-	Antitoxin
- (2185084)	2185084..2185184	+	101	NuclAT_1	-	Antitoxin
- (2185084)	2185084..2185184	+	101	NuclAT_1	-	Antitoxin
MID01_RS11150 (2186175)	2186175..2186369	+	195	WP_004399291.1	hypothetical protein	-
MID01_RS11155 (2186409)	2186409..2188916	+	2508	WP_109962753.1	DNA-directed RNA polymerase YonO	-
MID01_RS11160 (2189180)	2189180..2189455	+	276	WP_072692660.1	HU family DNA-binding protein	-
MID01_RS11165 (2189878)	2189878..2189989	+	112	Protein_2154	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2116127..2265019	148892

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6859.40 Da
• Isoelectric Point: 12.8196

>T235977 WP_109962752.1 NZ_CP092369:c2185143-2184967 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRIRKRLRPKRQRQHIRR

Nucleotide

• Length: 177 bp

>T235977 NZ_LR134527:661176-661445 [Bartonella elizabethae]
TTGGTTTGGACGATTAGATATGAAAAAAAAGCTCTCAGTTTTTTAAAAAAATGCGATAAAAAAGAAGCGCGGCGGATTGT
TGATTTTTTAGATCAACAGATTGCTTCTCTTGAAGATGTGCGTACAATAGGAAAGCCTTTAAGAGGCCAGTTATCAGGTT
TGTGGAGATATCGTGTAGGAGATTATAGGATACTTTGCGAGCTTTATGATAAGGAGCTTGTCGTTTTAGTTTTGGCTGTT
GGACATAGAAAAAATATATATAAAAGCTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT235977 NZ_CP092369:2185084-2185184 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATAATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin