Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2101517..2101659 Replicon chromosome
Accession NZ_CP092184
Organism Serratia marcescens strain YHYF1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2101561..2101657 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2101517..2101659 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MF265_RS10165 (MF265_10165) 2096784..2097179 + 396 WP_048322942.1 RidA family protein -
MF265_RS10170 (MF265_10170) 2097336..2098289 + 954 WP_004928848.1 prolyl aminopeptidase -
MF265_RS10175 (MF265_10175) 2098322..2098552 - 231 WP_016928156.1 DNA polymerase III subunit theta -
MF265_RS10180 (MF265_10180) 2098897..2099415 + 519 WP_015377481.1 non-heme ferritin -
MF265_RS10185 (MF265_10185) 2099708..2100124 + 417 WP_046686875.1 CopC domain-containing protein YobA -
MF265_RS10190 (MF265_10190) 2100127..2101008 + 882 WP_239044467.1 copper homeostasis membrane protein CopD -
MF265_RS10195 (MF265_10195) 2101078..2101419 + 342 WP_049300694.1 YebY family protein -
- 2101517..2101659 - 143 - - Antitoxin
- 2101561..2101657 + 97 - - Toxin
MF265_RS10200 (MF265_10200) 2101744..2102823 - 1080 WP_239044468.1 phage integrase Arm DNA-binding domain-containing protein -
MF265_RS10205 (MF265_10205) 2102759..2103067 - 309 WP_239044469.1 excisionase -
MF265_RS10210 (MF265_10210) 2103130..2104482 - 1353 WP_239044470.1 class I SAM-dependent methyltransferase -
MF265_RS10215 (MF265_10215) 2104561..2104872 - 312 WP_239044471.1 hypothetical protein -
MF265_RS10220 (MF265_10220) 2105092..2105289 - 198 WP_239044472.1 hypothetical protein -
MF265_RS10225 (MF265_10225) 2105406..2105936 + 531 WP_239044473.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2091429..2118478 27049


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T235768 NZ_CP092184:2101561-2101657 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 143 bp

>AT235768 NZ_CP092184:c2101659-2101517 [Serratia marcescens]
ATAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References