Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4610731..4610876 | Replicon | chromosome |
| Accession | NZ_CP091650 | ||
| Organism | Klebsiella pneumoniae strain TAKPN-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4610767..4610869 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4610731..4610876 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L6D56_RS22235 | 4605861..4607921 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| L6D56_RS22240 | 4607925..4608584 | - | 660 | WP_021440386.1 | exodeoxyribonuclease X | - |
| L6D56_RS22245 | 4608663..4608893 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| L6D56_RS22250 | 4609006..4609380 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| L6D56_RS22255 | 4609384..4610253 | + | 870 | WP_021440385.1 | copper homeostasis membrane protein CopD | - |
| L6D56_RS22260 | 4610270..4610608 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 4610731..4610876 | - | 146 | - | - | Antitoxin |
| - | 4610767..4610869 | + | 103 | - | - | Toxin |
| L6D56_RS22265 | 4611245..4611388 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| L6D56_RS22270 | 4611493..4612461 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| L6D56_RS22275 | 4612618..4613271 | + | 654 | WP_021440384.1 | protein-serine/threonine phosphatase | - |
| L6D56_RS22280 | 4613268..4613459 | - | 192 | WP_002911395.1 | YebW family protein | - |
| L6D56_RS22285 | 4613557..4613796 | - | 240 | WP_002911393.1 | YebV family protein | - |
| L6D56_RS22290 | 4613912..4615345 | - | 1434 | WP_021440382.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T234217 NZ_CP091650:4610767-4610869 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT234217 NZ_CP091650:c4610876-4610731 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT