Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4610731..4610876 Replicon chromosome
Accession NZ_CP091650
Organism Klebsiella pneumoniae strain TAKPN-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4610767..4610869 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4610731..4610876 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6D56_RS22235 4605861..4607921 + 2061 WP_004151449.1 oligopeptidase B -
L6D56_RS22240 4607925..4608584 - 660 WP_021440386.1 exodeoxyribonuclease X -
L6D56_RS22245 4608663..4608893 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L6D56_RS22250 4609006..4609380 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L6D56_RS22255 4609384..4610253 + 870 WP_021440385.1 copper homeostasis membrane protein CopD -
L6D56_RS22260 4610270..4610608 + 339 WP_002911404.1 YebY family protein -
- 4610731..4610876 - 146 - - Antitoxin
- 4610767..4610869 + 103 - - Toxin
L6D56_RS22265 4611245..4611388 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L6D56_RS22270 4611493..4612461 - 969 WP_014907334.1 VirK/YbjX family protein -
L6D56_RS22275 4612618..4613271 + 654 WP_021440384.1 protein-serine/threonine phosphatase -
L6D56_RS22280 4613268..4613459 - 192 WP_002911395.1 YebW family protein -
L6D56_RS22285 4613557..4613796 - 240 WP_002911393.1 YebV family protein -
L6D56_RS22290 4613912..4615345 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T234217 NZ_CP091650:4610767-4610869 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT234217 NZ_CP091650:c4610876-4610731 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References