Detailed information of TA system TA234128

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3538408..3538800
• Replicon: chromosome
• Accession: NZ_CP091630
• Organism: Salmonella enterica strain 1147

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: L5506_RS17130
• Protein ID: WP_241467015.1
• Coordinates: 3538555..3538800 (+)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3538408..3538764 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5506_RS17100	3533660..3534157	-	498	WP_165963407.1	pilus assembly protein	-
L5506_RS17105	3534919..3535623	-	705	Protein_3348	integrase core domain-containing protein	-
L5506_RS17110	3535676..3535990	+	315	WP_133322996.1	SymE family type I addiction module toxin	-
L5506_RS17115	3536057..3536335	-	279	WP_133323248.1	hypothetical protein	-
L5506_RS17120	3536653..3537120	-	468	WP_000828178.1	sugar tyrosine-protein kinase	-
L5506_RS17125	3537938..3538357	-	420	WP_131040133.1	hypothetical protein	-
-	3538408..3538764	-	357	-	-	Antitoxin
L5506_RS17130	3538555..3538800	+	246	WP_241467015.1	hypothetical protein	Toxin
L5506_RS17135	3538867..3539409	-	543	WP_079984650.1	hypothetical protein	-
L5506_RS17140	3539409..3543515	-	4107	WP_133322998.1	RHS repeat-associated core domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3525755..3539409	13654

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 8848.00 Da
• Isoelectric Point: 4.0543

>T234128 WP_241467015.1 NZ_CP091630:3538555-3538800 [Salmonella enterica]
MNASDVSVRHINSETCMTACYSQIPSGDCQEEAGFETGRSVTVKISDGCIVLMADGNEVQKLCEQLYQAEQVVKGMWDVI
V

Nucleotide

• Length: 246 bp

>T234128 NZ_LR027516:1253707-1254081 [Mycobacterium tuberculosis]
GTGATCCTGGTCGACACTTCGGTATGGATTGAGCACCTGCGCGCCGCCGACGCGCGACTCGTCGAGCTGCTGGGCGATGA
CGAGGCCGGTTGCCATCCGCTCGTCATCGAGGAGCTGGCGCTTGGCTCGATCAAGCAGCGAGACGTTGTTCTCGATCTGT
TGGCCAACCTCTACCAGTTTCCGGTGGTGACCCACGACGAAGTGTTGCGGCTTGTCGGTCGGCGGCGGTTGTGGGGTCGG
GGACTCGGTGCCGTCGATGCCAACCTTCTTGGTTCGGTGGCTCTGGTTGGCGGCGCGCGACTATGGACGCGGGACAAGCG
GTTGAAGGCGGCGTGCGCGGAAAGCGGTGTTGCGCTGGCTGAGGAAGTGTCCTGA

Antitoxin

Nucleotide

• Length: 357 bp

>AT234128 NZ_CP091630:c3538764-3538408 [Salmonella enterica]
TTCAGCCTGATAAAGCTGTTCGCACAGCTTCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCT
TCACCGTCACGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGCGGTC
ATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGACGTCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTC
CGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAGCGAGTATGGGCGCGACATCCTGGCATCGCGCCTCTCTCTCCCCG
GCCAGTGATGAGCAACCGGCTGCCGGGGCCGTATTTT

Structures

Antitoxin