Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1404607..1405137 Replicon chromosome
Accession NZ_CP090635
Organism Burkholderia contaminans strain FFI45

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LXE92_RS06525 Protein ID WP_256946690.1
Coordinates 1404898..1405137 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LXE92_RS06520 Protein ID WP_089456200.1
Coordinates 1404607..1404852 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXE92_RS06495 (LXE92_06485) 1400813..1401079 + 267 WP_105815832.1 type II toxin-antitoxin system VapB family antitoxin -
LXE92_RS06500 (LXE92_06490) 1401076..1401237 + 162 WP_223274361.1 type II toxin-antitoxin system VapC family toxin -
LXE92_RS06505 (LXE92_06495) 1401387..1401860 - 474 Protein_1271 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
LXE92_RS06510 (LXE92_06500) 1401829..1402917 - 1089 WP_278130000.1 type IV toxin-antitoxin system AbiEi family antitoxin -
LXE92_RS06515 (LXE92_06505) 1403275..1404490 + 1216 Protein_1273 M20 family metallopeptidase -
LXE92_RS06520 (LXE92_06510) 1404607..1404852 + 246 WP_089456200.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LXE92_RS06525 (LXE92_06515) 1404898..1405137 + 240 WP_256946690.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LXE92_RS06530 (LXE92_06520) 1405208..1406511 - 1304 Protein_1276 cobyrinate a,c-diamide synthase -
LXE92_RS06535 (LXE92_06525) 1406514..1407116 - 603 WP_046545692.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
LXE92_RS06540 (LXE92_06530) 1407154..1407531 - 378 WP_039358613.1 cobalamin biosynthesis protein -
LXE92_RS06545 (LXE92_06535) 1407528..1408410 - 883 Protein_1279 uroporphyrinogen-III C-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-74)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9295.64 Da        Isoelectric Point: 8.0671

>T231534 WP_256946690.1 NZ_CP090635:1404898-1405137 [Burkholderia contaminans]
IWRDTVGRGSLKQADLYHRDLIGTMEALARGEKVGRTCIVRDGYFRYAVGSHVVFYRETEYTIDLIRVLHQRMDIEQHL

Download         Length: 240 bp

>T231534 NZ_CP126927:c4308-4003 [Escherichia coli O2:K1:H5]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGTTGTCAGATAAGGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAGGAAGTG
GCTGATCTCAGCCACCGAGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9034.99 Da        Isoelectric Point: 5.6864

>AT231534 WP_089456200.1 NZ_CP090635:1404607-1404852 [Burkholderia contaminans]
MSQNTSVSRRDHFAELVDTQVQSEQYGSASDVERTGLRLLESRDMQVRALQEALKAGEVSGAPRPFDREAFLARMRAAHD
G

Download         Length: 246 bp

>AT231534 NZ_CP126927:c4528-4310 [Escherichia coli O2:K1:H5]
ATGAAGCAGCGCATTACAGTCACCGTCGACAGTGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGGCT
GGTAAGCACCACCCTGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCAGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGACGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References