Detailed information of TA system TA231390

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 368698..369229
• Replicon: chromosome
• Accession: NZ_CP090597
• Organism: Pectobacterium aroidearum strain QJ002

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: A0A1V2R9S3
• Locus tag: L0Y24_RS01630
• Protein ID: WP_012822123.1
• Coordinates: 368942..369229 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: L0Y24_RS01625
• Protein ID: WP_180778477.1
• Coordinates: 368698..368952 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y24_RS01600 (L0Y24_01600)	363857..364447	-	591	WP_012773024.1	DnaA initiator-associating protein DiaA	-
L0Y24_RS01605 (L0Y24_01605)	364489..364884	-	396	WP_256599989.1	YraN family protein	-
L0Y24_RS01610 (L0Y24_01610)	364842..366860	-	2019	WP_256599289.1	penicillin-binding protein activator	-
L0Y24_RS01615 (L0Y24_01615)	366922..367809	+	888	WP_256599290.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
L0Y24_RS01625 (L0Y24_01625)	368698..368952	+	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
L0Y24_RS01630 (L0Y24_01630)	368942..369229	+	288	WP_012822123.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L0Y24_RS01635 (L0Y24_01635)	369408..370193	+	786	WP_256599291.1	4,5-DOPA dioxygenase extradiol	-
L0Y24_RS01640 (L0Y24_01640)	370263..371423	-	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
L0Y24_RS01645 (L0Y24_01645)	371435..372109	-	675	WP_012773030.1	DUF1190 family protein	-
L0Y24_RS01650 (L0Y24_01650)	372377..373768	-	1392	WP_182100458.1	outer membrane channel protein TolC	-
L0Y24_RS01655 (L0Y24_01655)	373903..374058	-	156	WP_012773032.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10997.94 Da
• Isoelectric Point: 10.7694

>T231390 WP_012822123.1 NZ_CP090597:368942-369229 [Pectobacterium aroidearum]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTKGRSA

Nucleotide

• Length: 288 bp

>T231390 NZ_CP126345:1882202-1882453 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT231390 WP_180778477.1 NZ_CP090597:368698-368952 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT231390 NZ_CP126345:1882450-1882704 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Structures

Toxin

• AlphaFold DB: A0A1V2R9S3