Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995230..1995374 Replicon chromosome
Accession NC_011283
Organism Klebsiella pneumoniae 342

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1995266..1995368 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995230..1995374 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPK_RS09270 1990360..1992420 + 2061 WP_012541258.1 oligopeptidase B -
KPK_RS09275 1992424..1993083 - 660 WP_012541259.1 exodeoxyribonuclease X -
KPK_RS09280 1993162..1993392 - 231 WP_012541260.1 DNA polymerase III subunit theta -
KPK_RS09285 1993506..1993880 + 375 WP_012541261.1 CopC domain-containing protein YobA -
KPK_RS09290 1993884..1994753 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
KPK_RS09295 1994770..1995108 + 339 WP_008804271.1 YebY family protein -
- 1995230..1995374 - 145 - - Antitoxin
- 1995266..1995368 + 103 - - Toxin
KPK_RS30940 1995753..1995896 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
KPK_RS09305 1996000..1996989 - 990 WP_032691211.1 VirK/YbjX family protein -
KPK_RS09310 1997125..1997778 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
KPK_RS09315 1997775..1997966 - 192 WP_002911395.1 YebW family protein -
KPK_RS09320 1998064..1998303 - 240 WP_002911393.1 YebV family protein -
KPK_RS09325 1998419..1999852 - 1434 WP_012541265.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T23094 NC_011283:1995266-1995368 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT23094 NC_011283:c1995374-1995230 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References