Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2894914..2895953 Replicon chromosome
Accession NZ_CP090381
Organism Achromobacter deleyi strain SMAs-55

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag LYZ39_RS13425 Protein ID WP_171663605.1
Coordinates 2895378..2895953 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag LYZ39_RS13420 Protein ID WP_171663606.1
Coordinates 2894914..2895381 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LYZ39_RS13405 (LYZ39_13405) 2890691..2892031 - 1341 WP_171663609.1 MFS transporter -
LYZ39_RS13410 (LYZ39_13410) 2892106..2893767 - 1662 WP_171663608.1 choline dehydrogenase -
LYZ39_RS13415 (LYZ39_13415) 2893899..2894756 + 858 WP_171663607.1 IclR family transcriptional regulator -
LYZ39_RS13420 (LYZ39_13420) 2894914..2895381 + 468 WP_171663606.1 helix-turn-helix domain-containing protein Antitoxin
LYZ39_RS13425 (LYZ39_13425) 2895378..2895953 + 576 WP_171663605.1 PIN domain-containing protein Toxin
LYZ39_RS13430 (LYZ39_13430) 2895943..2897028 - 1086 WP_171663604.1 methyltransferase -
LYZ39_RS13435 (LYZ39_13435) 2897185..2898105 + 921 WP_171663603.1 AraC family transcriptional regulator -
LYZ39_RS13440 (LYZ39_13440) 2898267..2900402 + 2136 WP_234103404.1 metallophosphoesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21354.30 Da        Isoelectric Point: 5.9902

>T230532 WP_171663605.1 NZ_CP090381:2895378-2895953 [Achromobacter deleyi]
VRHSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSPQIHDEWKRNLLSNRGDLTSEQLDRTSALMDRAIPDGLVTGH
ETLIAGLSLPDPDDRHVLAAAIRCSASVIVTFNQKDFPAAALDPYGIEAQHPDEFVENLFDLDQAAVVSAAQRQRAQLKN
PTMDVNRYLDVLLRQGLVQTVKALSTYQAIL

Download         Length: 576 bp

>T230532 NZ_CP124918:2807090-2807230 [Enterococcus faecalis]
ATTTCTCTGAAAAATACGAATAAAAATATCGTTTACTGTACAACATATGAAACAATTCAGACGATCCTAGGGTTTGGTAT
GTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17384.86 Da        Isoelectric Point: 5.2709

>AT230532 WP_171663606.1 NZ_CP090381:2894914-2895381 [Achromobacter deleyi]
MPHTALSKMVLPVEREVEAAVQGQRALAAYLATRFETQSIQILDDQNQAHNVELPTSALRLLVDILAELADGNAVQVVPI
HAELTTQEAADLLNVSRPHIVKLLEEGLLPFHRTGKHRRVRFADLMQFKAERERASEQAMEELARQAQELAMGYE

Download         Length: 468 bp

>AT230532 NZ_CP124918:c2807361-2807163 [Enterococcus faecalis]
TTTTTAGGTAATTGTGCTATAATGGTAATGAAAAGAGAGCTATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTAAGA
CGGTGACCTTTTTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References