Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4783441..4784033 Replicon chromosome
Accession NZ_CP090244
Organism Serratia marcescens strain SMNSF-1

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag LXH15_RS23055 Protein ID WP_049300714.1
Coordinates 4783683..4784033 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag LXH15_RS23050 Protein ID WP_016930357.1
Coordinates 4783441..4783689 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXH15_RS23030 (LXH15_23030) 4779259..4779597 + 339 WP_016930352.1 PTS lactose/cellobiose transporter subunit IIA -
LXH15_RS23035 (LXH15_23035) 4779594..4780901 + 1308 WP_016930353.1 6-phospho-beta-glucosidase -
LXH15_RS23040 (LXH15_23040) 4780974..4781954 + 981 WP_079450511.1 LacI family DNA-binding transcriptional regulator -
LXH15_RS23045 (LXH15_23045) 4782146..4783330 + 1185 WP_004930336.1 MFS transporter TsgA -
LXH15_RS23050 (LXH15_23050) 4783441..4783689 + 249 WP_016930357.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LXH15_RS23055 (LXH15_23055) 4783683..4784033 + 351 WP_049300714.1 type II toxin-antitoxin system ChpB family toxin Toxin
LXH15_RS23060 (LXH15_23060) 4784030..4785313 - 1284 WP_234213245.1 cytosine deaminase -
LXH15_RS23065 (LXH15_23065) 4785602..4788151 + 2550 WP_234213247.1 nitrite reductase large subunit NirB -
LXH15_RS23070 (LXH15_23070) 4788148..4788474 + 327 WP_016930361.1 nitrite reductase small subunit NirD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-82)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12404.41 Da        Isoelectric Point: 11.5657

>T230358 WP_049300714.1 NZ_CP090244:4783683-4784033 [Serratia marcescens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVIADALARLQAIID

Download         Length: 351 bp

>T230358 NZ_CP124883:51025-51135 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9083.56 Da        Isoelectric Point: 4.5026

>AT230358 WP_016930357.1 NZ_CP090244:4783441-4783689 [Serratia marcescens]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALIIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT230358 NZ_CP124883:c51239-51175 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References