Detailed information of TA system TA229987

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 405046..405577
• Replicon: chromosome
• Accession: NZ_CP090065
• Organism: Pectobacterium polonicum strain BY21311

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: LW347_RS01895
• Protein ID: WP_137740637.1
• Coordinates: 405290..405577 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: LW347_RS01890
• Protein ID: WP_137740636.1
• Coordinates: 405046..405300 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LW347_RS01865 (LW347_01865)	400525..401115	-	591	WP_005975525.1	DnaA initiator-associating protein DiaA	-
LW347_RS01870 (LW347_01870)	401157..401513	-	357	WP_193555653.1	YraN family protein	-
LW347_RS01875 (LW347_01875)	401510..403528	-	2019	WP_258883818.1	penicillin-binding protein activator	-
LW347_RS01880 (LW347_01880)	403590..404477	+	888	WP_258883819.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
LW347_RS01890 (LW347_01890)	405046..405300	+	255	WP_137740636.1	plasmid stabilization protein	Antitoxin
LW347_RS01895 (LW347_01895)	405290..405577	+	288	WP_137740637.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LW347_RS01900 (LW347_01900)	405754..406539	+	786	WP_258883820.1	4,5-DOPA dioxygenase extradiol	-
LW347_RS01905 (LW347_01905)	406595..407158	-	564	WP_137740639.1	sel1 repeat family protein	-
LW347_RS01910 (LW347_01910)	407311..408471	-	1161	WP_258883821.1	glutathionylspermidine synthase family protein	-
LW347_RS01915 (LW347_01915)	408483..409151	-	669	WP_258883822.1	DUF1190 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-74)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10939.85 Da
• Isoelectric Point: 10.7694

>T229987 WP_137740637.1 NZ_CP090065:405290-405577 [Pectobacterium polonicum]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLAERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDEVITVMVMGGGK
REGSQIYSDTKGRSA

Nucleotide

• Length: 288 bp

>T229987 NZ_CP124655:c3232614-3232036 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAGCGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTTTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCGGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
GCCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGACCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGTTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9179.43 Da
• Isoelectric Point: 3.9370

>AT229987 WP_137740636.1 NZ_CP090065:405046-405300 [Pectobacterium polonicum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGKTVDDRMSELADAKEIS
LDDL

Nucleotide

• Length: 255 bp

>AT229987 NZ_CP124655:c3233256-3232702 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA