Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2348061..2348332 Replicon chromosome
Accession NZ_CP089272
Organism Escherichia coli O157:H7 strain M1300706001A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2348191..2348294 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2348061..2348332 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LSI73_RS11995 2344616..2345278 - 663 WP_000944244.1 exodeoxyribonuclease X -
LSI73_RS12000 2345302..2345958 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
LSI73_RS12005 2346060..2346290 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LSI73_RS12010 2346429..2346803 + 375 WP_000168751.1 CopC domain-containing protein YobA -
LSI73_RS12015 2346807..2347679 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
LSI73_RS12020 2347692..2348033 + 342 WP_000976483.1 YebY family protein -
- 2348061..2348332 - 272 - - Antitoxin
- 2348191..2348294 + 104 - - Toxin
LSI73_RS12025 2348429..2349085 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
LSI73_RS12030 2349086..2349277 - 192 WP_001296140.1 YebW family protein -
LSI73_RS12035 2349382..2349618 - 237 WP_001295499.1 YebV family protein -
LSI73_RS12040 2349736..2351175 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T227949 NZ_CP089272:2348191-2348294 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT227949 NZ_CP089272:c2348332-2348061 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References