Detailed information of TA system TA022742

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1573378..1574011
• Replicon: chromosome
• Accession: NC_010506
• Organism: Shewanella woodyi ATCC 51908

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: B1KI49
• Locus tag: SWOO_RS06280
• Protein ID: WP_012323873.1
• Coordinates: 1573598..1574011 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: SWOO_RS06275
• Protein ID: WP_041417516.1
• Coordinates: 1573378..1573617 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SWOO_RS06250	1568727..1569530	+	804	WP_041417515.1	sulfite exporter TauE/SafE family protein	-
SWOO_RS06255	1569622..1570473	+	852	WP_012323869.1	thymidylate synthase	-
SWOO_RS06260	1570780..1571980	+	1201	Protein_1230	Na+/H+ antiporter NhaA	-
SWOO_RS06265	1571977..1572360	+	384	WP_012323870.1	hypothetical protein	-
SWOO_RS06270	1572382..1573290	+	909	WP_012323871.1	transcriptional activator NhaR	-
SWOO_RS06275	1573378..1573617	+	240	WP_041417516.1	succinate dehydrogenase assembly factor 2	Antitoxin
SWOO_RS06280	1573598..1574011	+	414	WP_012323873.1	hypothetical protein	Toxin
SWOO_RS06285	1574039..1575649	-	1611	WP_012323874.1	L-aspartate oxidase	-
SWOO_RS06290	1575850..1576428	+	579	WP_012323875.1	RNA polymerase sigma factor RpoE	-
SWOO_RS06295	1576463..1577065	+	603	WP_012323876.1	anti-sigma factor	-
SWOO_RS06300	1577115..1578047	+	933	WP_012323877.1	MucB/RseB C-terminal domain-containing protein	-
SWOO_RS06305	1578062..1578517	+	456	WP_012323878.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-135)

Antitoxin

• Flavinator of succinate dehydrogenase (4-74)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15997.67 Da
• Isoelectric Point: 6.6940

>T22742 WP_012323873.1 NC_010506:1573598-1574011 [Shewanella woodyi ATCC 51908]
VEETQHSFNLTSSFDQRFSLVVFASLCLTSFLAWPLLDSLLYHLIKALFFSIMLLFFIHQFLQLKSWRFQFVLNGAGEGR
LQGEERFKLTQKAFVSPFVCLFYIEADEKQTLMIVWSDMCDDTSYRNLCRLLLASKG

Nucleotide

• Length: 414 bp

>T22742 NC_010506:1573598-1574011 [Shewanella woodyi ATCC 51908]
GTGGAAGAGACGCAGCATAGCTTTAATCTCACCTCGTCATTCGACCAGCGTTTCTCGTTGGTCGTTTTTGCCAGTCTATG
TTTAACCTCATTTCTTGCGTGGCCCCTGTTAGATTCACTCCTATATCACCTGATTAAAGCGCTGTTTTTCTCGATTATGC
TGCTGTTTTTTATCCATCAGTTTTTACAACTCAAGAGTTGGCGTTTTCAATTTGTGCTTAATGGGGCTGGGGAGGGACGT
TTGCAGGGGGAGGAGAGGTTTAAGTTAACGCAAAAGGCGTTTGTTTCCCCCTTTGTTTGCCTGTTCTATATTGAAGCTGA
TGAAAAGCAGACGTTAATGATAGTGTGGTCTGATATGTGTGACGACACAAGTTACCGAAACTTGTGCCGTCTTTTGCTTG
CCAGTAAAGGCTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9332.94 Da
• Isoelectric Point: 6.7100

>AT22742 WP_041417516.1 NC_010506:1573378-1573617 [Shewanella woodyi ATCC 51908]
MNIARVRWACRRGMLELDVLFQPFVEKHYEQMSVEDKHIFVRLLEGEDPVLFAWFMGHEKCADPELAKMVIRVRGRDAA

Nucleotide

• Length: 240 bp

>AT22742 NC_010506:1573378-1573617 [Shewanella woodyi ATCC 51908]
ATGAATATCGCTAGAGTTAGATGGGCTTGTCGCAGAGGAATGTTGGAGCTTGATGTTCTCTTCCAACCATTTGTTGAAAA
ACATTACGAGCAGATGTCCGTTGAAGATAAACATATTTTTGTTCGTCTGTTAGAGGGTGAAGATCCGGTATTGTTTGCTT
GGTTTATGGGCCATGAAAAATGCGCTGATCCTGAGCTCGCTAAGATGGTGATCCGTGTCCGTGGAAGAGACGCAGCATAG

Structures

Toxin

• AlphaFold DB: B1KI49