Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 9667..10208 Replicon chromosome
Accession NZ_CP088953
Organism Microbulbifer elongatus strain DSM 6810

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LRR79_RS00050 Protein ID WP_231758404.1
Coordinates 9906..10208 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LRR79_RS00045 Protein ID WP_231758403.1
Coordinates 9667..9909 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRR79_RS00030 5524..7008 - 1485 WP_231758400.1 DEAD/DEAH box helicase -
LRR79_RS00035 7488..8399 + 912 WP_231758401.1 bile acid:sodium symporter -
LRR79_RS00040 8469..9116 + 648 WP_231758402.1 prolyl oligopeptidase family serine peptidase -
LRR79_RS00045 9667..9909 + 243 WP_231758403.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LRR79_RS00050 9906..10208 + 303 WP_231758404.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LRR79_RS00055 10318..10914 - 597 WP_231758405.1 HEPN domain-containing protein -
LRR79_RS00060 11190..13076 - 1887 WP_231758406.1 DNA topoisomerase IV subunit B -
LRR79_RS00065 13123..13767 - 645 WP_231758407.1 YqiA/YcfP family alpha/beta fold hydrolase -
LRR79_RS00070 13834..14496 - 663 WP_231758408.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11284.03 Da        Isoelectric Point: 10.3758

>T227166 WP_231758404.1 NZ_CP088953:9906-10208 [Microbulbifer elongatus]
MSSFKLSRKAKSDLKGIANFTERRWGVAQRNVYIKKFDDAFHDLAASPLSGVSSENIKSGYRKIPHGAHIIFYKIGESDC
VEIIRILHQSMDVKSKLLST

Download         Length: 303 bp

>T227166 NZ_CP122758:696358-696735 [Escherichia coli]
ATGAAAACATTACCCGACACGCATGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGATACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTGGAAAAATACGCACTGGTACGAACCGACCAGCCGGGGTTC
AGCACCTGTACCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8894.83 Da        Isoelectric Point: 4.2815

>AT227166 WP_231758403.1 NZ_CP088953:9667-9909 [Microbulbifer elongatus]
MAKNTSITLGSHFDEFIAKEVASGRYGSASEVVRAGLRLLEDTETKLETLRSLLQEGEESGFTDYTYESFIAELDDKKTP

Download         Length: 243 bp

>AT227166 NZ_CP122758:695900-696268 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGTGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATTCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTCAGCCCCCGCCATCAGCATACCGTGACACTGTATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References