Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4899827..4900072 Replicon chromosome
Accession NZ_CP087880
Organism Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)


Gene name hokX Uniprot ID L4J2K8
Locus tag G163CM_RS22870 Protein ID WP_000956460.1
Coordinates 4899920..4900072 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 4899827..4899875 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G163CM_RS22855 4895270..4897072 + 1803 WP_231826386.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
G163CM_RS22860 4897072..4898784 + 1713 WP_231826387.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
G163CM_RS22865 4898921..4899655 + 735 WP_231826388.1 phosphoadenosine phosphosulfate reductase -
- 4899827..4899875 - 49 - - Antitoxin
G163CM_RS22870 4899920..4900072 + 153 WP_000956460.1 Hok/Gef family protein Toxin
G163CM_RS22875 4900139..4901182 - 1044 WP_015963245.1 aminopeptidase -
G163CM_RS22880 4901431..4902837 + 1407 WP_231828416.1 siroheme synthase CysG -
G163CM_RS22885 4902847..4903755 + 909 WP_015963247.1 sulfate adenylyltransferase subunit CysD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5602.81 Da        Isoelectric Point: 7.7899

>T226470 WP_000956460.1 NZ_CP087880:4899920-4900072 [Pseudocitrobacter corydidari]
MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

>T226470 NZ_CP122496:3373854-3374072 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 49 bp

>AT226470 NZ_CP087880:c4899875-4899827 [Pseudocitrobacter corydidari]
GTTCGAACGCGAGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829G7J5

Antitoxin

Download structure file

References