Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1135878..1136367 Replicon chromosome
Accession NZ_CP087814
Organism Moraxella bovis strain SAM109238

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP088_RS06085 Protein ID WP_112742208.1
Coordinates 1136110..1136367 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP088_RS06080 Protein ID WP_228157840.1
Coordinates 1135878..1136120 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP088_RS06045 (LP088_06010) 1130978..1132027 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP088_RS06050 (LP088_06015) 1132146..1132943 + 798 WP_264676262.1 polyphenol oxidase family protein -
LP088_RS06055 1132940..1133152 + 213 WP_264676263.1 bestrophin family protein -
LP088_RS06060 (LP088_06020) 1133142..1133660 + 519 WP_264676264.1 bestrophin family protein -
LP088_RS06065 (LP088_06025) 1133823..1135056 + 1234 Protein_1184 DUF853 family protein -
LP088_RS06070 (LP088_06030) 1135300..1135587 + 288 WP_078273310.1 DUF1315 family protein -
LP088_RS06075 (LP088_06035) 1135669..1135833 - 165 WP_162860378.1 hypothetical protein -
LP088_RS06080 (LP088_06040) 1135878..1136120 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP088_RS06085 (LP088_06045) 1136110..1136367 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP088_RS06090 (LP088_06050) 1136426..1136935 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP088_RS06095 (LP088_06055) 1137001..1137804 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP088_RS06100 (LP088_06060) 1137900..1140422 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226248 WP_112742208.1 NZ_CP087814:1136110-1136367 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226248 NZ_CP122320:1329499-1329852 [Pantoea agglomerans pv. gypsophilae]
ATGTGGGATGTGGATACAACCAAAAGATTTGATGAGTGGTTTAAGGCTCAGAGTGAGGAACTGAAGGAGGATATGCTCGC
TGCGATAGTTATCCTGTCTGAGTATGGGCCGCATTTAGCGAGGCCGTTTGCTGATACCGTAGACGGCTCTCATTTTCCGA
ATATGAAAGAATTAAGAGTGCAGCATCAAGGCAAACCGATACGGGCCTTCTTTGCTTTTGATCCTTCTCGCCGCGGCATT
GTGTTGTGTGCAGGCGATAAAACCGGGGTTAAGGAAAAGAAATTCTATAAAGACATGATCAAATTGGCAGATGCTGAATT
CCGCAAATATTTGAATGGAGGGGATAATGGCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226248 WP_228157840.1 NZ_CP087814:1135878-1136120 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226248 NZ_CP122320:1329845-1330144 [Pantoea agglomerans pv. gypsophilae]
ATGGCTAATTTAAAAGAGCTGATGGCAAATCAAAGTCCGGAGAGTCGCGAACGCATTGCCAAAAAAGTCGATGCAATGCG
GCAGGTTATCGCGCTACACATGTTGCGCGAAGAACTTAACCTGTCACAGACAGAGATGGCGTACGCAATGGGTGTGAAAC
AGCCAACTATCGCCAGAATGGAACAGGCTGATAATGATCCCCGCCTTTCTACGCTGAAGCGTTACGTTACGGCTCTGGGA
GGCGAGATAAGTATCGATGTCAAATTGCCGACAGGCAAAAGAATAGCTTTTGATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References