Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 891945..892522 Replicon chromosome
Accession NZ_CP087781
Organism Moraxella bovis strain SAM57978

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP129_RS04660 Protein ID WP_078275234.1
Coordinates 892187..892522 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP129_RS04655 Protein ID WP_078275235.1
Coordinates 891945..892187 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP129_RS04630 (LP129_04600) 887844..888266 - 423 WP_078275239.1 hypothetical protein -
LP129_RS04635 (LP129_04605) 888275..888580 - 306 WP_078275238.1 YciI family protein -
LP129_RS04640 (LP129_04610) 888740..889366 - 627 WP_078275237.1 septation protein IspZ -
LP129_RS04645 (LP129_04615) 889555..890277 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP129_RS04650 (LP129_04620) 890659..891738 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP129_RS04655 (LP129_04625) 891945..892187 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP129_RS04660 (LP129_04630) 892187..892522 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP129_RS04665 (LP129_04635) 892584..893579 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP129_RS04670 (LP129_04640) 893651..893839 + 189 WP_143821748.1 hypothetical protein -
LP129_RS04675 (LP129_04645) 893929..896073 - 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP129_RS04680 (LP129_04650) 896238..896822 - 585 WP_112741954.1 hypothetical protein -
LP129_RS04685 (LP129_04655) 896982..897182 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226131 WP_078275234.1 NZ_CP087781:892187-892522 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226131 NZ_CP122315:c2682993-2682886 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226131 WP_078275235.1 NZ_CP087781:891945-892187 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226131 NZ_CP122315:2683040-2683106 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References