Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2001260..2001405 Replicon chromosome
Accession NZ_CP087629
Organism Klebsiella pneumoniae subsp. pneumoniae strain DD02341

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2001296..2001398 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2001260..2001405 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMH53_RS09770 (LMH53_09770) 1996390..1998450 + 2061 WP_004151449.1 oligopeptidase B -
LMH53_RS09775 (LMH53_09775) 1998454..1999113 - 660 WP_002911407.1 exodeoxyribonuclease X -
LMH53_RS09780 (LMH53_09780) 1999192..1999422 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LMH53_RS09785 (LMH53_09785) 1999535..1999909 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LMH53_RS09790 (LMH53_09790) 1999913..2000782 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LMH53_RS09795 (LMH53_09795) 2000799..2001137 + 339 WP_002911404.1 YebY family protein -
- 2001260..2001405 - 146 - - Antitoxin
- 2001296..2001398 + 103 - - Toxin
LMH53_RS09800 (LMH53_09800) 2001773..2001916 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LMH53_RS09805 (LMH53_09805) 2002021..2002989 - 969 WP_004151446.1 VirK/YbjX family protein -
LMH53_RS09810 (LMH53_09810) 2003146..2003799 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LMH53_RS09815 (LMH53_09815) 2003796..2003987 - 192 WP_002911395.1 YebW family protein -
LMH53_RS09820 (LMH53_09820) 2004085..2004324 - 240 WP_002911393.1 YebV family protein -
LMH53_RS09825 (LMH53_09825) 2004440..2005873 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225733 NZ_CP087629:2001296-2001398 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT225733 NZ_CP087629:c2001405-2001260 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References