Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2540246..2540514 Replicon chromosome
Accession NZ_CP087294
Organism Escherichia coli strain APEC E956

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2540284..2540386 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2540246..2540514 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LO740_RS12485 2537403..2538842 + 1440 WP_001317885.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LO740_RS12490 2538960..2539196 + 237 WP_001295499.1 YebV family protein -
LO740_RS12495 2539301..2539492 + 192 WP_001317886.1 YebW family protein -
LO740_RS12500 2539493..2540149 - 657 WP_000812744.1 protein-serine/threonine phosphatase -
- 2540246..2540514 + 269 - - Antitoxin
- 2540284..2540386 - 103 - - Toxin
LO740_RS12505 2540544..2540885 - 342 WP_000976472.1 YebY family protein -
LO740_RS12510 2540898..2541770 - 873 WP_000879316.1 copper homeostasis membrane protein CopD -
LO740_RS12515 2541774..2542148 - 375 WP_000168747.1 CopC domain-containing protein YobA -
LO740_RS12520 2542287..2542517 + 231 WP_000916759.1 DNA polymerase III subunit theta -
LO740_RS12525 2542619..2543275 + 657 WP_000011673.1 carbon-nitrogen hydrolase family protein YobB -
LO740_RS12530 2543299..2543961 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T225308 NZ_CP087294:c2540386-2540284 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT225308 NZ_CP087294:2540246-2540514 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References