Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 32884..33445 Replicon plasmid P2
Accession NZ_CP086981
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-111

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOE09_RS19975 Protein ID WP_224557555.1
Coordinates 32884..33159 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOE09_RS19980 Protein ID WP_224557554.1
Coordinates 33152..33445 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE09_RS19960 (LOE09_19955) 28673..29989 - 1317 WP_224557560.1 lactate racemase domain-containing protein -
LOE09_RS19965 (LOE09_19960) 30006..31553 - 1548 WP_224557559.1 altronate dehydratase family protein -
LOE09_RS19970 (LOE09_19965) 31645..32415 + 771 WP_224557557.1 GntR family transcriptional regulator -
LOE09_RS19975 (LOE09_19970) 32884..33159 - 276 WP_224557555.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOE09_RS19980 (LOE09_19975) 33152..33445 - 294 WP_224557554.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LOE09_RS19985 (LOE09_19980) 33516..34421 - 906 WP_224557552.1 dihydrodipicolinate synthase family protein -
LOE09_RS19990 (LOE09_19985) 34432..36171 - 1740 WP_224557550.1 L-arabinonate dehydratase -
LOE09_RS19995 (LOE09_19990) 36433..37968 + 1536 WP_224557548.1 aldehyde dehydrogenase (NADP(+)) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..82234 82234


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10108.67 Da        Isoelectric Point: 4.4912

>T224626 WP_224557555.1 NZ_CP086981:c33159-32884 [Pseudosulfitobacter pseudonitzschiae]
VPDLEWKALAVADLMAIVDYISDDNPDAAISLMDDIQDKVLGLLTHPKSGRPGRVNDTRELVIRPNYIVVYAENTAAVTI
LRVLHAVQMWP

Download         Length: 276 bp

>T224626 NZ_CP120367:c2204046-2203660 [Sinorhizobium numidicum]
ATGGTCATCGACACCTCCGCCATCGTCGCGATCGCATTCAATGAGCCGGAAGCGGAAAGCTACGAGCAAAAAGTCGTCGA
CGCTCCACGGCGCTTCATCTCGGCCGCGACAGTCCTTGAACTGGCAATCGTCATCGAGGCGCGCCTCGGCGAGGCAGGTG
CCGCCGAGCTCGATCTATGGCTCTACAAGGCGGGCGTCGAAATCGTCGCCGTCGACGCGGAGCAGATCGCCGTCGCAAGG
CGAGCCTGGCGCAGCTACGGCAAAGGCCGACATCCGGCAGGTCTGAATTATGGAGACTGTTTCTCCTATGCGCTGGCCAA
GACGCGCAACGAACCGCTGCTCTTCAAAGGTGATGATTTCTCACGCACCGACATGCAGGCGGCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10166.59 Da        Isoelectric Point: 7.2024

>AT224626 WP_224557554.1 NZ_CP086981:c33445-33152 [Pseudosulfitobacter pseudonitzschiae]
MSAQTSMIHVRVDDQLKAKATDALSGVGLTLSDAVRILLTRVAAEGGLPAGLTANPDAYDAWFRAKVQDALADAAPAKPH
DQVMRDARALIDGKRGA

Download         Length: 294 bp

>AT224626 NZ_CP120367:c2204300-2204046 [Sinorhizobium numidicum]
ATGGCGCTCAGCATTAAAGATCTAGAGACGGAACGCCTGGCAAAGGCACTGGCCGAGAAGACTGGTGAAACTATTACCAT
GGCGACCCGCCGCGCACTGGAAGAGCGGCTGCGGCGTCTCGCAAACACGGGAAATCGCGATGTTCTTCTCGAGGAGCTTG
CCGCCAGCCGTCGACGCTGGGCGAAGCTGCCGGTGCTCGACAACCGCTCTGCCGATGAGATTTTGGGGTATGACGAAAAC
GGGCTCCCCAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References