Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 264066..264226 Replicon chromosome
Accession NZ_CP086654
Organism Staphylococcus ratti strain CCM 9025

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag LN051_RS01120 Protein ID WP_229292800.1
Coordinates 264066..264167 (+) Length 34 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 264192..264226 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN051_RS01100 (LN051_01100) 259787..260218 + 432 WP_229292797.1 antibiotic biosynthesis monooxygenase -
LN051_RS01105 (LN051_01105) 260511..261980 - 1470 WP_229292798.1 HAMP domain-containing sensor histidine kinase -
LN051_RS01110 (LN051_01110) 261973..262650 - 678 WP_229292799.1 response regulator transcription factor -
LN051_RS01115 (LN051_01115) 262873..263877 + 1005 Protein_221 HoxN/HupN/NixA family nickel/cobalt transporter -
LN051_RS01120 (LN051_01120) 264066..264167 + 102 WP_229292800.1 type I toxin-antitoxin system Fst family toxin Toxin
- 264192..264226 - 35 - - Antitoxin
LN051_RS01125 (LN051_01125) 264355..264615 - 261 WP_229292801.1 DUF2316 family protein -
LN051_RS01130 (LN051_01130) 264886..265302 + 417 WP_229292802.1 hypothetical protein -
LN051_RS01135 (LN051_01135) 265441..266058 + 618 WP_229292803.1 DedA family protein -
LN051_RS01140 (LN051_01140) 266222..266875 - 654 WP_229292804.1 hypothetical protein -
LN051_RS01145 (LN051_01145) 267090..268538 + 1449 WP_274704567.1 alkaline phosphatase -
LN051_RS01150 (LN051_01150) 268804..269196 + 393 WP_229292805.1 (deoxy)nucleoside triphosphate pyrophosphohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(14-56)


Sequences

Toxin        


Download         Length: 34 a.a.        Molecular weight: 3822.63 Da        Isoelectric Point: 10.4935

>T224278 WP_229292800.1 NZ_CP086654:264066-264167 [Staphylococcus ratti]
MLEILVHITATIISGCIVALFTHWLRTRDNKKK

Download         Length: 102 bp

>T224278 NZ_CP119980:c909278-909021 [Salmonella enterica]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCGAAACCTGCATGACCACCAGTTACTCACATATCCCCAGCCA
GCACCTTAAGGGTGACTGGCAGGAAGAAGCGGGATTTGAGACCGGGCGCAGCGTGACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAACAGCTTTACAAGGCTGAACAGGTGGTTAAGGGGATG
CGGGACGTGATTGTTTAG

Antitoxin


Download         Length: 35 bp

>AT224278 NZ_CP086654:c264226-264192 [Staphylococcus ratti]
ACACCAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References